Evaluation of the degradation of two bioabsorbable interference screws: an in-vivo study in sheep

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Autor(es): dc.contributorFaculty of Veterinary Medicine-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorUniversidade de Marília-
Autor(es): dc.contributorVeterinary Medicine School-
Autor(es): dc.creatorScorsato, Paulo Sérgio-
Autor(es): dc.creatorRahal, Sheila Canevese-
Autor(es): dc.creatorCestari, Tania Mary-
Autor(es): dc.creatorMamprim, Maria Jaqueline-
Autor(es): dc.creatorDoiche, Danuta Pulz-
Autor(es): dc.creatorTeixeira, Daniel de Bortoli-
Autor(es): dc.creatorSiqueira, Rafael Cerântola-
Autor(es): dc.creatorFelix, Marcílio-
Data de aceite: dc.date.accessioned2025-08-21T15:11:57Z-
Data de disponibilização: dc.date.available2025-08-21T15:11:57Z-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2021-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1590/acb370405-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/241262-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/241262-
Descrição: dc.descriptionPurpose: To evaluate in-vivo degradation of two bioabsorbable interference screws. Methods: Twenty-two crossbred Santa Inês ewes were used. A poly-DL-lactide (PDLLA) screw (70%/30%) was inserted in the right pelvic limb, and a PDLLA screw (70%) + β-tri-calcium phosphate (β-TCP) (30%) in the left pelvic limb. Animals were euthanized at one, four, seven and a half and 18 months after surgery. Plain radiography, computed tomography (CT), microCT, and histological analysis were accomplished. Results: PDLLA screw was hypodense at all evaluation moments, but with progressive density increase along the central axis, whereas PDLLA/β-TCP was initially hyperdense and progressively lost this characteristic. No adverse reactions were observed on histological evaluation. Conclusions: The inclusion of β-TCP favors screw degradation since the PDLLA/β-TCP screws evidenced a more intense degradation process than the PDLLA screws at the last evaluation. PDLLA screws showed higher bone production, evident around the screw thread, inside the lateral perforations, and in the central canal, whereas the PDLLA/β-TCP screws presented less bone tissue at the implantation site.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionUniversidade de Marília Faculty of Veterinary Medicine Department of Veterinary Surgery and Anesthesiology, SP-
Descrição: dc.descriptionUniversidade Estadual Paulista “Júlio de Mesquita Filho” School of Veterinary Medicine and Animal Science Department of Veterinary Surgery and Animal Reproduction, SP-
Descrição: dc.descriptionUniversidade de São Paulo Bauru School of Dentistry Department of Biological Sciences, SP-
Descrição: dc.descriptionUniversidade de Marília Department of Agronomic Engineering, Marília, SP-
Descrição: dc.descriptionUniversidade de Marília Veterinary Medicine School, Marília, SP-
Descrição: dc.descriptionUniversidade Estadual Paulista “Júlio de Mesquita Filho” School of Veterinary Medicine and Animal Science Department of Veterinary Surgery and Animal Reproduction, SP-
Descrição: dc.descriptionCAPES: 001-
Idioma: dc.languageen-
Relação: dc.relationActa Cirurgica Brasileira-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAbsorbable Implants-
Palavras-chave: dc.subjectBone Screws-
Palavras-chave: dc.subjectPolylactic Acid-Polyglycolic Acid Copolymer-
Palavras-chave: dc.subjectSheep-
Título: dc.titleEvaluation of the degradation of two bioabsorbable interference screws: an in-vivo study in sheep-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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