Meiotic behavior, transmission and active genes of B chromosomes in the cichlid Astatotilapia latifasciata: new clues about nature, evolution and maintenance of accessory elements

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversity of Würzburg-
Autor(es): dc.creatorCardoso, Adauto Lima-
Autor(es): dc.creatorVenturelli, Natália Bortholazzi-
Autor(es): dc.creatorda Cruz, Irene-
Autor(es): dc.creatorde Sá Patroni, Fábio Malta-
Autor(es): dc.creatorde Moraes, Diogo-
Autor(es): dc.creatorde Oliveira, Rogério Antonio-
Autor(es): dc.creatorBenavente, Ricardo-
Autor(es): dc.creatorMartins, Cesar-
Data de aceite: dc.date.accessioned2025-08-21T21:37:25Z-
Data de disponibilização: dc.date.available2025-08-21T21:37:25Z-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2022-07-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s00438-022-01911-4-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/241165-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/241165-
Descrição: dc.descriptionSupernumerary B chromosomes (Bs) are dispensable genetic elements widespread in eukaryotes and are poorly understood mainly in relation to mechanisms of maintenance and transmission. The cichlid Astatotilapia latifasciata can harbor Bs in a range of 0 (named B −) and 1–2 (named B +). The B in A. latifasciata is rich in several classes of repetitive DNA sequences, contains protein coding genes, and affects hosts in diverse ways, including sex-biased effects. To advance in the knowledge about the mechanisms of maintenance and transmission of B chromosomes in A. latifasciata, here, we studied the meiotic behavior in males and transmission rates of A. latifasciata B chromosome. We also analyzed structurally and functionally the predicted B chromosome copies of the cell cycle genes separin-like, tubb1-like and kif11-like. We identified in the meiotic structure relative to the B chromosome the presence of proteins associated with Synaptonemal Complex organization (SMC3, SYCP1 and SYCP3) and found that the B performs self-pairing. These data suggest that isochromosome formation was a step during B chromosome evolution and this element is in a stage of diversification of the two arms keeping the self-pairing behavior to protect the A chromosome complement of negative effects of recombination. Moreover, we observed no occurrence of B-drive and confirmed the presence of cell cycle genes copies in the B chromosome and their transcription in encephalon, muscle and gonads, which can indicates beneficial effects to hosts and contribute to B maintenance.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionDeutsches Forschungszentrum für Gesundheit und Umwelt, Helmholtz Zentrum München-
Descrição: dc.descriptionDepartment of Structural and Functional Biology Institute of Biosciences at Botucatu Sao Paulo State University UNESP, SP-
Descrição: dc.descriptionDepartment of Cell and Developmental Biology Biocenter University of Würzburg-
Descrição: dc.descriptionDepartment of Biostatistics Plant Biology Parasitology and Zoology Institute of Biosciences at Botucatu Sao Paulo State University UNESP-
Descrição: dc.descriptionDepartment of Structural and Functional Biology Institute of Biosciences at Botucatu Sao Paulo State University UNESP, SP-
Descrição: dc.descriptionDepartment of Biostatistics Plant Biology Parasitology and Zoology Institute of Biosciences at Botucatu Sao Paulo State University UNESP-
Descrição: dc.descriptionFAPESP: 2013/19898-7-
Descrição: dc.descriptionFAPESP: 2013/25234-4-
Descrição: dc.descriptionFAPESP: 2014/15756-6-
Descrição: dc.descriptionFAPESP: 2015/16661-1-
Descrição: dc.descriptionFAPESP: 2016/03912-9-
Descrição: dc.descriptionFAPESP: 2016/07743-7-
Descrição: dc.descriptionFAPESP: 2017/07484-4-
Descrição: dc.descriptionCNPq: 304111/2020-1-
Descrição: dc.descriptionCNPq: 305321/2015-3-
Descrição: dc.descriptionDeutsches Forschungszentrum für Gesundheit und Umwelt, Helmholtz Zentrum München: Be1168/8-1-
Formato: dc.format1151-1167-
Idioma: dc.languageen-
Relação: dc.relationMolecular Genetics and Genomics-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectActive B-genes-
Palavras-chave: dc.subjectHeterotic model-
Palavras-chave: dc.subjectSupernumerary chromosome-
Palavras-chave: dc.subjectSynaptonemal complex-
Título: dc.titleMeiotic behavior, transmission and active genes of B chromosomes in the cichlid Astatotilapia latifasciata: new clues about nature, evolution and maintenance of accessory elements-
Tipo de arquivo: dc.typelivro digital-
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