Association between pre-operative complications, comorbidities, and in-hospital mortality in a hip fracture cohort: a register study in a tertiary hospital in Brazil

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorQueen’s University-
Autor(es): dc.contributorUniversity of Nottingham-
Autor(es): dc.creatorSouza, Andre Moreira Fogaça de-
Autor(es): dc.creatorMacola, Abner-
Autor(es): dc.creatorGumieiro, David Nicoletti-
Autor(es): dc.creatorNicolodi, Gustavo Augusto-
Autor(es): dc.creatorLima, Rodrigo Moreira e-
Autor(es): dc.creatorMinicucci, Marcos Ferreira-
Autor(es): dc.creatorAzevedo, Paula Schmidt-
Autor(es): dc.creatorSahota, Opinder-
Autor(es): dc.creatorLima, Lais Helena Navarro e-
Data de aceite: dc.date.accessioned2025-08-21T19:00:42Z-
Data de disponibilização: dc.date.available2025-08-21T19:00:42Z-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2022-08-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s00264-022-05443-9-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/241047-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/241047-
Descrição: dc.descriptionPurpose: The incidence of hip fractures is increasing exponentially due to an aging Brazilian population. Older people had significant comorbidities which increases the risk of post-operative mortality. Our purpose was to examine the association between pre-operative infections and comorbidities on the risk of post-operative in-hospital mortality after proximal femur fracture surgery’s, beyond that, to evaluate the association between comorbidities and time to surgery. Methods: This is a population-based cohort retrospective study, using medical records of all six year consecutive surgical procedures for correction of hip fracture in a tertiary teaching Hospital in Brazil. The exclusion criteria aimed to exclusively allocate patients who had their first hip fracture secondary to low-energy trauma. Multivariate logistical regression was performed and receiver operating characteristic (ROC) curve with area under curve (AUC) to evaluate the sensitivity and specificity of the model. p-value < 0.05 was considered significant. Results: Final sample was composed by 856 consecutive patients with 81 years of median and 164 patients were excluded. The median length of hospital say was five days with − l mortality at 3.6%. Significant variables for increased mortality included the presence of pre-operative infection (odds ratio (OR): 3.9(1.12–8.54), chronic obstructive pulmonary disease (COPD) (OR: 3.83(1.36–10.82)), and systemic arterial hypertension (SAH) (OR: 4.1(1.18–14.25)). Development of pre-operative infection was associated with a delay to surgery (OR: 1.1 (1.08–1.13)). Conclusions: In older people with proximal femur fracture, the presence of pre-operative infection, COPD and SAH were the strongest risk factor for post-operative in-hospital mortality. Pre-operative infection was associated with statistically significant delay to surgery.-
Descrição: dc.descriptionAnesthesiology Department Botucatu Medical School São Paulo State University-
Descrição: dc.descriptionSurgery and Orthopedic Department Botucatu Medical School São Paulo State University UNESP-
Descrição: dc.descriptionAnesthesiology Department Queen’s University-
Descrição: dc.descriptionInternal Medicine Department Botucatu Medical School São Paulo State University UNESP, Rubiao Junior s/n, SP, CEP-
Descrição: dc.descriptionOrthogeriatric Medicine University of Nottingham-
Descrição: dc.descriptionAnesthesiology Department Botucatu Medical School São Paulo State University-
Descrição: dc.descriptionSurgery and Orthopedic Department Botucatu Medical School São Paulo State University UNESP-
Descrição: dc.descriptionInternal Medicine Department Botucatu Medical School São Paulo State University UNESP, Rubiao Junior s/n, SP, CEP-
Formato: dc.format1873-1880-
Idioma: dc.languageen-
Relação: dc.relationInternational Orthopaedics-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectChronic obstructive pulmonary disease-
Palavras-chave: dc.subjectComorbidities-
Palavras-chave: dc.subjectHip fracture-
Palavras-chave: dc.subjectRisk factors-
Palavras-chave: dc.subjectSystemic arterial hypertension-
Título: dc.titleAssociation between pre-operative complications, comorbidities, and in-hospital mortality in a hip fracture cohort: a register study in a tertiary hospital in Brazil-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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