Quaternary bioactive glass-derived powders presenting submicrometric particles and antimicrobial activity

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Autor(es): dc.contributorUniversidade Federal de São Carlos (UFSCar)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorFriedrich-Alexander-Universität Erlangen-Nürnberg-
Autor(es): dc.creatorNovak, Sara-
Autor(es): dc.creatorOrives, Juliane Resges-
Autor(es): dc.creatorNalin, Marcelo-
Autor(es): dc.creatorUnalan, Irem-
Autor(es): dc.creatorBoccaccini, Aldo R.-
Autor(es): dc.creatorCamargo, Emerson R. de-
Data de aceite: dc.date.accessioned2025-08-21T23:29:06Z-
Data de disponibilização: dc.date.available2025-08-21T23:29:06Z-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2022-10-15-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.ceramint.2022.06.266-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/240424-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/240424-
Descrição: dc.descriptionThe biomedical engineering advances in the last years have been rising demand for multifunctional biomaterials. Bioactive glass (BG) submicron particles are potential candidates for the formulation of composites with improved dispersion and homogeneity between the constituents. This work presents the preparation of SiO2–Na2O–CaO–P2O5 glass-derived powders composed of particles with homogenous shapes and sizes between 300 and 500 nm. Two types of synthesis were employed for the preparation of the BG powders, the melt-quenching method, and a citric acid-assisted sol-gel route at a low citric acid concentration (0.005 mol L−1). The morphology of the particles was achieved by a low-energy process using a ball mill. These powders were characterized for their structure and surface area and evaluated for in vitro mineralization and antibacterial behavior. X-ray diffraction (XRD) analysis revealed different crystalline silicate phases in the sol-gel-derived powder and confirmed the amorphous structure of the melt-quenching-derived one. The surface of the particles was covered by hydroxycarbonate-apatite (HCA) after five days in simulated body fluid (SBF). The antibacterial activity against Staphylococcus aureus was higher for the sol-gel-derived powder, showing inhibition >99% of the bacteria growth in 24 h for all concentrations studied. These BG-based powders present a set of characteristics useful for the formulation of multifunctional composites for orthopedic applications.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionDeutscher Akademischer Austauschdienst-
Descrição: dc.descriptionDepartment of Chemistry Federal University of São Carlos (UFSCar) Rod. Washington Luis km 235 CP 676, São Carlos-
Descrição: dc.descriptionSão Paulo State University (UNESP) Institute of Chemistry, Rua Prof. Francisco Degni 55-
Descrição: dc.descriptionInstitute of Biomaterials Department of Materials Science and Engineering Friedrich-Alexander-Universität Erlangen-Nürnberg, Cauerstrasse 6-
Descrição: dc.descriptionSão Paulo State University (UNESP) Institute of Chemistry, Rua Prof. Francisco Degni 55-
Descrição: dc.descriptionCAPES: 001-
Descrição: dc.descriptionFAPESP: 2013/07296-2-
Descrição: dc.descriptionFAPESP: 2013/07793-6-
Descrição: dc.descriptionFAPESP: 2019/19609-1-
Descrição: dc.descriptionCNPq: 309711/2019-3-
Descrição: dc.descriptionDeutscher Akademischer Austauschdienst: 57552395-
Formato: dc.format29982-29990-
Idioma: dc.languageen-
Relação: dc.relationCeramics International-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAntimicrobial glass-
Palavras-chave: dc.subjectBioactive glass-ceramic particles-
Palavras-chave: dc.subjectIon release-
Palavras-chave: dc.subjectMineralization-
Título: dc.titleQuaternary bioactive glass-derived powders presenting submicrometric particles and antimicrobial activity-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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