Development of an Antibacterial Dentin Adhesive

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorFederal University of Espírito Santo-
Autor(es): dc.contributorThe Fourth Military Medical University-
Autor(es): dc.contributorAugusta University-
Autor(es): dc.creatorLopes, Stephanie R.-
Autor(es): dc.creatorMatuda, Amanda G. N.-
Autor(es): dc.creatorCampos, Raquel P.-
Autor(es): dc.creatorMafetano, Ana Paula V. P.-
Autor(es): dc.creatorBarnabe, Ana Helena M.-
Autor(es): dc.creatorChagas, Gabriela S.-
Autor(es): dc.creatorBarcellos, Daphne C.-
Autor(es): dc.creatorNiu, Li-Na-
Autor(es): dc.creatorTay, Franklin R.-
Autor(es): dc.creatorPucci, Cesar R.-
Data de aceite: dc.date.accessioned2025-08-21T23:47:08Z-
Data de disponibilização: dc.date.available2025-08-21T23:47:08Z-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2022-06-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/polym14122502-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/240355-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/240355-
Descrição: dc.descriptionNisin is a peptide that possesses potent antibacterial properties. This study evaluated the antibacterial activity of a nisin-doped adhesive against Streptococcus mutans, as well as its degree of conversion and microtensile bond strength (µTBS) to dentin. Nisin was added to the adhesive Adper Single Bond 2 (3M ESPE), resulting in four groups: Control Group (Single Bond 2); Group 1% (1 wt% nisin-incorporated), Group 3% (3 wt% nisin-incorporated) and Group 5% (5 wt% nisin-incorporated). Antibacterial activity against S. mutans was evaluated using colony-forming unit counts (CFU). The degree of conversion was tested using FTIR. Forty human teeth were restored for µTBS evaluation. Data were statistically analyzed with ANOVA and Tukey tests at α = 0.05. The nisin-doped adhesives, for all concentrations, exhibited a significant inhibition of the growth of S. mutans (p < 0.05); Incorporation of 5% and 3% nisin decreased the degree of conversion of the adhesive (p < 0.05). The µTBS (in MPa): Control Group—38.3 ± 2.3A, Group 1%—35.6 ± 2.1A, Group 3%—27.1 ± 1.6B and Group 5%—22.3 ± 1.0C. Nisin-doped adhesives exerted a bactericidal effect on S. mutans. The µTBS and degree of conversion of adhesive were not affected after incorporation of 1% nisin.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionDepartment of Restorative Dentistry Institute of Science and Technology São Paulo State University (UNESP), São Paulo-
Descrição: dc.descriptionDepartment of Prosthodontics Federal University of Espírito Santo, Espírito Santo-
Descrição: dc.descriptionState Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases & Shaanxi Key Laboratory of Stomatology Department of Prosthodontics School of Stomatology The Fourth Military Medical University-
Descrição: dc.descriptionDepartment of Endodontics The Dental College of Georgia Augusta University-
Descrição: dc.descriptionDepartment of Restorative Dentistry Institute of Science and Technology São Paulo State University (UNESP), São Paulo-
Descrição: dc.descriptionFAPESP: 2019/01626-7-
Idioma: dc.languageen-
Relação: dc.relationPolymers-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectantibacterial activity-
Palavras-chave: dc.subjectdentin-
Palavras-chave: dc.subjectetch-and-rinse adhesive-
Palavras-chave: dc.subjectnisin-
Título: dc.titleDevelopment of an Antibacterial Dentin Adhesive-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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