Open flap debridement compared to repeated applications of photodynamic therapy in the treatment of residual pockets: A randomized clinical trial

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorGuarulhos University (UNG)-
Autor(es): dc.contributorUniversidade Estadual de Campinas (UNICAMP)-
Autor(es): dc.contributorUniversity of Kentucky-
Autor(es): dc.creatorAndere, Naira M. R. B.-
Autor(es): dc.creatorSantos, Nídia C. Castro dos-
Autor(es): dc.creatorAraújo, Cássia F.-
Autor(es): dc.creatorPaz, Hélvis E. S.-
Autor(es): dc.creatorShaddox, Luciana M.-
Autor(es): dc.creatorCasarin, Renato C. V.-
Autor(es): dc.creatorSantamaria, Mauro P.-
Data de aceite: dc.date.accessioned2025-08-21T22:42:45Z-
Data de disponibilização: dc.date.available2025-08-21T22:42:45Z-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2021-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1002/JPER.22-0059-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/240180-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/240180-
Descrição: dc.descriptionBackground: The aim of the present study was to compare repeated applications of antimicrobial photodynamic therapy (aPDT) to open flap debridement (OFD) in the treatment of residual periodontal pockets in non-furcation sites. Methods: Forty-six subjects with a diagnosis of Stage III or IV Grade C periodontitis, that had been previously treated, participated in the study. Residual pockets were divided between two groups: (1) aPDT group: received ultrasonic periodontal debridement followed by immediate application of aPDT, and repeated on1st, 2nd, 7th, and 14th days; and (2) OFD group: treated by modified papilla preservation technique, where granulation tissue and visible calculus were removed with hand curettes and an ultrasonic device. Clinical, immunological, and microbiological parameters were evaluated before and after treatment. Results: Both treatments were effective reducing clinical parameters of disease. OFD resulted in a greater mean probing pocket depths (PPD) reduction in deep pockets (p = 0.001). However, aPDT resulted in a lower occurrence of gingival recession (GR), dentin hypersensitivity (DH) and analgesic intake. Reduction in Porphyromonas gingivalis was observed in both groups. Only the OFD group had a significant reduction in Aggregatibacter actinomycetemcomitans. aPDT group had greater increase in interleukin 10 (IL-10) levels and a greater reduction of interleukin 1 beta (IL-1β) at 14 days when compared to the OFD group (p < 0.05). Conclusion: OFD was superior in reducing PPD in deep pockets compared to the aPDT. However, OFD resulted in greater GR. Both treatments lowered P. gingivalis levels but only OFD reduced levels of A. actinomycemtemcomitans.-
Descrição: dc.descriptionDivision of Periodontics Institute of Science and Technology São Paulo State University (Unesp), São Paulo-
Descrição: dc.descriptionDental Research Division Guarulhos University (UNG), São Paulo-
Descrição: dc.descriptionDivision of Periodontics Piracicaba Dental School University of Campinas (Unicamp), São Paulo-
Descrição: dc.descriptionDivision of Periodontology College of Dentistry University of Kentucky-
Descrição: dc.descriptionDivision of Periodontics Institute of Science and Technology São Paulo State University (Unesp), São Paulo-
Idioma: dc.languageen-
Relação: dc.relationJournal of Periodontology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectantiinfective agents-
Palavras-chave: dc.subjectgingival recession-
Palavras-chave: dc.subjectperiodontal debridement-
Palavras-chave: dc.subjectperiodontal pocket-
Palavras-chave: dc.subjectperiodontitis-
Palavras-chave: dc.subjectphotodynamic therapy-
Palavras-chave: dc.subjectsurgical procedure-
Palavras-chave: dc.subjectultrasonic-
Título: dc.titleOpen flap debridement compared to repeated applications of photodynamic therapy in the treatment of residual pockets: A randomized clinical trial-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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