Physicochemical properties and osteoclastogenesis for three premixed calcium silicate-based sealers post set

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Autor(es): dc.contributorUniversidade Federal de Uberlândia (UFU)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorDe Rosatto, Camila Maria Peres-
Autor(es): dc.creatorSouza, Gabriela Leite de-
Autor(es): dc.creatorFerraz, Danilo Cassiano-
Autor(es): dc.creatorSilva, Marcelo José Barbosa-
Autor(es): dc.creatorTanomaru-Filho, Mario-
Autor(es): dc.creatorMoura, Camilla Christian Gomes-
Data de aceite: dc.date.accessioned2025-08-21T15:22:04Z-
Data de disponibilização: dc.date.available2025-08-21T15:22:04Z-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2023-03-01-
Data de envio: dc.date.issued2021-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1590/1807-3107bor-2022.vol36.0065-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/240045-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/240045-
Descrição: dc.descriptionSolubility, pH, ion release, cytotoxicity, and osteoclastogenesis inhibition in bone marrow-derived monocyte macrophages (BMMs) were evaluated in EndoSequence BC Sealer (END), Bio-C Sealer (BC), and Sealer Plus BC (SPBC). pH was determined after immersion of the sealers in deionized water (DW) and Minimum Essential Medium Alpha (α-MEM). Solubility was obtained by mass loss. Ion release was measured by using X-ray fluorescence spectroscopy (XRF). Cytotoxicity was evaluated by MTT assay. Inhibition of osteoclastogenesis was evaluated by tartrate-resistant acid phosphatase (TRAP). Data were analyzed using the t-test, ANOVA and Tukey/Dunnett’s post-hoc tests (α = 0.05). END had the highest pH in DW (p < 0.05), and BC, in α-MEM (p < 0.05). Solubility in DW was the lowest for SPBC (p < 0.005). The highest calcium release was observed for BC in DW at 12 h (p < 0.05), and in α-MEM at 12 and 24 h (p < 0.05). The lowest toxicity was detected for END (p < 0.05). BC had the highest inhibitory effect on osteoclasts (p < 0.05). Overall, the highest solubility and pH values were found in DW. However, the calcium silicate-based sealer showed higher solubility than the ISO standards. Calcium release was the highest for BC. END showed the highest cell viability, and BC, the highest osteoclast inhibition.-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionUniversidade Federal de Uberlândia – UFU School of Dentistry Department of Endodontics, MG-
Descrição: dc.descriptionUniversidade Estadual Paulista – Unesp School of Dentistry Department of Restorative Dentistry, SP-
Descrição: dc.descriptionUniversidade Federal de Uberlândia – UFU Institute of Biomedical Sciences Department of Immunology, MG-
Descrição: dc.descriptionUniversidade Estadual Paulista – Unesp School of Dentistry Department of Restorative Dentistry, SP-
Idioma: dc.languageen-
Relação: dc.relationBrazilian Oral Research-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectEndodontics-
Palavras-chave: dc.subjectMaterials testing-
Palavras-chave: dc.subjectOsteogenesis-
Palavras-chave: dc.subjectRoot canal filling materials-
Título: dc.titlePhysicochemical properties and osteoclastogenesis for three premixed calcium silicate-based sealers post set-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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