Worker bees (Apis mellifera) deprived of pollen in the first week of adulthood exhibit signs of premature aging

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorUniversidade Federal de São Carlos (UFSCar)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorMonash Univ-
Autor(es): dc.creatorMartelli, Felipe-
Autor(es): dc.creatorFalcon, Tiago-
Autor(es): dc.creatorPinheiro, Daniel G.-
Autor(es): dc.creatorSimoes, Zila L. P.-
Autor(es): dc.creatorNunes, Francis M. F.-
Data de aceite: dc.date.accessioned2025-08-21T20:24:57Z-
Data de disponibilização: dc.date.available2025-08-21T20:24:57Z-
Data de envio: dc.date.issued2022-11-29-
Data de envio: dc.date.issued2022-11-29-
Data de envio: dc.date.issued2022-07-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.ibmb.2022.103774-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/237757-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/237757-
Descrição: dc.descriptionPollinator populations, including bees, are in rapid decline in many parts of the world, raising concerns over the future of ecosystems and food production. Among the factors involved in these declines, poor nutrition deserves attention. The diet consumed by adult worker honeybees (Apis mellifera) is crucial for their behavioral maturation, i.e., the progressive division of labor they perform, such as nurse bees initially and later in life as foragers. Poor pollen nutrition is known to reduce the workers' lifespan, but the underlying physiological and genetic mechanisms are not fully understood. Here we investigate how the lack of pollen in the diet of workers during their first week of adult life can affect age-related phenotypes. During the first seven days of adult life, newly emerged workers were fed either a pollen-deprived (PD) diet mimicking that of an older bee, or a control pollenrich (PR) diet, as typically consumed by young bees. The PD-fed bees showed alterations in their fat body transcriptome, such as a switch from a protein-lipid based metabolism to a carbohydrate-based metabolism, and a reduced expression of genes involved with immune response. The absence of pollen in the diet also led to an accumulation of oxidative stress markers in fat body tissue and alterations in the cuticular hydrocarbon profiles, which became similar to those of chronologically older bees. Together, our data indicate that the absence of pollen during first week of adulthood triggers the premature onset of an aging-related worker phenotype.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionUniv Sao Paulo, Fac Med Ribeirao Preto, Dept Genet, Ave Bandeirantes 3900, BR-14049900 Ribeirao Preto, SP, Brazil-
Descrição: dc.descriptionUniv Sao Paulo, Fac Filosofia Ciencias & Letras Ribeirao Preto, Dept Biol, Ave Bandeirantes 3900, BR-14049900 Ribeirao Preto, SP, Brazil-
Descrição: dc.descriptionUniv Fed Sao Carlos, Ctr Ciencias Biol & Saude, Dept Genet & Evolucao, Rod Washington Luis km 235, BR-13565905 Sao Carlos, SP, Brazil-
Descrição: dc.descriptionUniv Estadual Paulista, Fac Ciencias Agr & Vet, Dept Tecnol, Via Acesso Prof Paulo Donato Castelane s-n, BR-14884900 Brazi, SP, Brazil-
Descrição: dc.descriptionMonash Univ, Sch Biol Sci, Clayton, Vic 3800, Australia-
Descrição: dc.descriptionUniv Estadual Paulista, Fac Ciencias Agr & Vet, Dept Tecnol, Via Acesso Prof Paulo Donato Castelane s-n, BR-14884900 Brazi, SP, Brazil-
Descrição: dc.descriptionFAPESP: 2010/10027-5-
Descrição: dc.descriptionFAPESP: 11/03171-5-
Descrição: dc.descriptionFAPESP: 12/24284-5-
Descrição: dc.descriptionFAPESP: 12/02757-9-
Descrição: dc.descriptionFAPESP: 07/07594-2-
Descrição: dc.descriptionCNPq: 461711/2014-1-
Descrição: dc.descriptionCNPq: 481000/2009-7-
Descrição: dc.descriptionCNPq: 161917/2011-9-
Descrição: dc.descriptionCAPES: 001-
Descrição: dc.descriptionCAPES: 88887.160608/2017-00-
Formato: dc.format11-
Idioma: dc.languageen-
Publicador: dc.publisherElsevier B.V.-
Relação: dc.relationInsect Biochemistry And Molecular Biology-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectHoney bees-
Palavras-chave: dc.subjectNutrition-
Palavras-chave: dc.subjectPollen-
Palavras-chave: dc.subjectOxidative stress-
Palavras-chave: dc.subjectCuticular hydrocarbons-
Palavras-chave: dc.subjectTranscriptome-
Palavras-chave: dc.subjectAging-
Título: dc.titleWorker bees (Apis mellifera) deprived of pollen in the first week of adulthood exhibit signs of premature aging-
Tipo de arquivo: dc.typelivro digital-
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