Calcium pretreatment enhances fluoride reactivity with enamel and dentine

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniv Michigan Sch Dent-
Autor(es): dc.contributorUniv Michigan-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorSpinola, Manuela Da Silva-
Autor(es): dc.creatorTenuta, Livia Maria Andalo-
Data de aceite: dc.date.accessioned2025-08-21T20:10:45Z-
Data de disponibilização: dc.date.available2025-08-21T20:10:45Z-
Data de envio: dc.date.issued2022-11-29-
Data de envio: dc.date.issued2022-11-29-
Data de envio: dc.date.issued2022-01-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.archoralbio.2021.105338-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/237555-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/237555-
Descrição: dc.descriptionObjective: High fluoride concentration treatments are known to react with enamel and dentine forming calcium fluoride (CaF2)-like deposits, but strategies to improve this reactivity beyond increasing fluoride concentration/ reducing pH in fluoride treatments have not been explored. Here we investigated the ability of a calcium pretreatment to improve fluoride reactivity.& nbsp;Design: In a blind and randomized in vitro study, sound and carious enamel and dentine slabs (n = 11/group) were randomly allocated into one of the following treatments: Deionized water (negative control); 0.05% sodium fluoride (F, positive control); 150 mM calcium lactate solution followed by 0.05% sodium fluoride solution (Ca-*F); 150 mM calcium lactate solution premixed with 0.05% sodium fluoride solution (CaF2, active control). Alkali-soluble fluoride (representing CaF2-like deposits formed on the substrates) was extracted from the slabs using 1 M KOH for 24 h and measured by an ion-specific electrode. Carious slabs were further observed under scanning electron microscopy (SEM). Data were analyzed by two-way ANOVA followed by Tukey test.& nbsp;Results: The Ca-*F treatment enhanced fluoride reactivity with all tested substrates when compared with F alone. Carious substrates had a greater reactivity with F and Ca-*F than their respective sound substrates, confirming that increased porosity enhances the reactivity with fluoride. Alkali-soluble fluoride concentration after the CaF(2 & nbsp;)treatment did not differ among the different substrates, suggesting this treatment causes only contamination with preformed CaF2, which was noted under SEM.& nbsp;Conclusion: A calcium pretreatment enhances the reactivity of fluoride with enamel and dentine.-
Descrição: dc.descriptionUniversity of Michigan College of Engineering and National Science Foundation (NSF, USA)-
Descrição: dc.descriptionUniv Michigan Sch Dent, Dept Cariol, Restorat Sci & Endodont, 1011 N Univ Ave, Ann Arbor, MI 48109 USA-
Descrição: dc.descriptionUniv Michigan, Dept Cariol Restorat Sci & Endodont, Sch Dent, 1011 N Univ Ave rm 2217, Ann Arbor, MI 48109 USA-
Descrição: dc.descriptionUniversity of Michigan College of Engineering and National Science Foundation (NSF, USA): DMR-1625671-
Formato: dc.format5-
Idioma: dc.languageen-
Publicador: dc.publisherElsevier B.V.-
Relação: dc.relationArchives Of Oral Biology-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectFluoride-
Palavras-chave: dc.subjectCalcium fluoride-
Palavras-chave: dc.subjectDental caries-
Palavras-chave: dc.subjectRoot-
Palavras-chave: dc.subjectPrevention-
Título: dc.titleCalcium pretreatment enhances fluoride reactivity with enamel and dentine-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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