Klebsiella-induced infections in domestic species: a case-series study in 697 animals (1997–2019)

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorAntonio Nariño University-
Autor(es): dc.contributorFATEC-
Autor(es): dc.creatorRibeiro, Márcio Garcia-
Autor(es): dc.creatorde Morais, Amanda Bonalume Cordeiro-
Autor(es): dc.creatorAlves, Ana Carolina-
Autor(es): dc.creatorBolaños, Carmen Alicia Daza-
Autor(es): dc.creatorde Paula, Carolina Lechinski-
Autor(es): dc.creatorPortilho, Fábio Vinicius Ramos-
Autor(es): dc.creatorde Nardi Júnior, Geraldo-
Autor(es): dc.creatorLara, Gustavo Henrique Batista-
Autor(es): dc.creatorde Souza Araújo Martins, Lorrayne-
Autor(es): dc.creatorMoraes, Lucieny Sierra-
Autor(es): dc.creatorRisseti, Rafaela Mastrangelo-
Autor(es): dc.creatorGuerra, Simony Trevizan-
Autor(es): dc.creatorBello, Thaís Spessotto-
Autor(es): dc.creatorSiqueira, Amanda Keller-
Autor(es): dc.creatorBertolini, Amanda Bezerra-
Autor(es): dc.creatorRodrigues, Carolina Aparecida-
Autor(es): dc.creatorPaschoal, Natália Rodrigues-
Autor(es): dc.creatorde Almeida, Beatriz Oliveira-
Autor(es): dc.creatorListoni, Fernando José Paganini-
Autor(es): dc.creatorSánchez, Luísa Fernanda García-
Autor(es): dc.creatorPaes, Antonio Carlos-
Data de aceite: dc.date.accessioned2025-08-21T21:31:37Z-
Data de disponibilização: dc.date.available2025-08-21T21:31:37Z-
Data de envio: dc.date.issued2022-05-01-
Data de envio: dc.date.issued2022-05-01-
Data de envio: dc.date.issued2022-03-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s42770-021-00667-0-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/233995-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/233995-
Descrição: dc.descriptionKlebsiella species, particularly K. pneumoniae, are well-known opportunistic enterobacteria related to complexity of clinical infections in humans and animals, commonly refractory to conventional therapy. The domestic animals may represent a source of the pathogenic and multidrug-resistant Klebsiella species to humans. Nevertheless, most studies involving Klebsiella-induced infections in domestic animals are restricted to case reports or outbreaks. We retrospectively investigated selected epidemiological data, clinical aspects, and in vitro susceptibility pattern of 697 non-repetitive Klebsiella infections in livestock and companion species (1997–2019). The isolates were obtained from different clinical disorders from dogs (n = 393), cattle (n = 149), horses (n = 98), cats (n = 27), pigs (n = 22), sheep (n = 5), goats (n = 2), and buffalo (n = 1), except four isolates from subclinical bovine mastitis. Urinary (223/697 = 32%), enteric (117/697 = 16.8%), mammary (85/697 = 12.2%), reproductive (85/697 = 12.2%), and respiratory disorders (67/697 = 9.6%) were the most common clinical manifestations. Other miscellaneous clinical pictures (116/697 = 16.6%) included abscesses, otitis, hepatitis, conjunctivitis, pyodermitis, sepsis, and encephalitis. Norfloxacin (183/245 = 74.7%) and gentamicin (226/330 = 68.5%) were the most effective antimicrobials. High in vitro resistance of the isolates was seen to ampicillin (326/355 = 91.8%), amoxicillin/clavulanic acid (25/62 = 40.3%), and trimethoprim/sulfamethoxazole (100/252 = 39.7), and multidrug resistance to ≥ 3 classes of antimicrobials was found in 20.4% (142/697) isolates. Wide variety of clinical manifestations of Klebsiella-induced infections was observed, with a predominance of urinary, enteric, mammary, reproductive, and respiratory tract disorders, reinforcing opportunistic behavior of agent. Poor in vitro efficacy was observed to some conventional antimicrobials and ~ 20% of isolates exhibited resistance pattern, reinforcing the need for proper use of drugs on therapy approaches in domestic animals to avoid multidrug-resistant bacteria, an emergent global concern.-
Descrição: dc.descriptionDepartment of Animal Production and Preventive Veterinary Medicine Sao Paulo State University-UNESP, SP-
Descrição: dc.descriptionSchool of Veterinary Medicine and Animal Science São Paulo State University-UNESP, SP-
Descrição: dc.descriptionDepartment of Veterinary Medicine Faculty of Veterinary Medicine and Animal Sciences Antonio Nariño University-
Descrição: dc.descriptionTechnology Faculty FATEC, SP-
Descrição: dc.descriptionDepartment of Animal Production and Preventive Veterinary Medicine Sao Paulo State University-UNESP, SP-
Descrição: dc.descriptionSchool of Veterinary Medicine and Animal Science São Paulo State University-UNESP, SP-
Formato: dc.format455-464-
Idioma: dc.languageen-
Relação: dc.relationBrazilian Journal of Microbiology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectClinical and epidemiological aspects-
Palavras-chave: dc.subjectCompanion animals-
Palavras-chave: dc.subjectKlebsiella pneumoniae-
Palavras-chave: dc.subjectLivestock-
Palavras-chave: dc.subjectMultidrug-resistant bacteria-
Título: dc.titleKlebsiella-induced infections in domestic species: a case-series study in 697 animals (1997–2019)-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.