Renal Magnesium Handling: A Comparison Between Dogs With Chronic Kidney Disease and Healthy Elderly Dogs

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorFranca University (UNIFRAN)-
Autor(es): dc.contributorUniversidade Federal de Uberlândia (UFU)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorde Lima, Charles Silva-
Autor(es): dc.creatorFerreira, Karina Rodrigues Gomes-
Autor(es): dc.creatorBorin-Crivellenti, Sofia-
Autor(es): dc.creatorMaia, Suellen Rodrigues-
Autor(es): dc.creatorSantana, Aureo Evangelista-
Autor(es): dc.creatorCrivellenti, Leandro Zuccolotto-
Data de aceite: dc.date.accessioned2025-08-21T21:09:02Z-
Data de disponibilização: dc.date.available2025-08-21T21:09:02Z-
Data de envio: dc.date.issued2022-05-01-
Data de envio: dc.date.issued2022-05-01-
Data de envio: dc.date.issued2021-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.tcam.2021.100588-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/233792-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/233792-
Descrição: dc.descriptionChronic kidney disease (CKD) and aging are known to possibly cause a progressive reduction in glomerular filtration rate, which may be associated with an increase in fractional excretion of electrolytes due to an adaptive response of the remaining functioning nephrons. However, the behavior of magnesium excretion has not been studied in CKD and healthy elderly dogs. The objective was to evaluate the fractional excretion of magnesium (FEMg) in dogs with (CKD) compared to healthy elderly dogs. Sixteen healthy elderly dogs and 43 dogs with CKD were divided into 3 groups (CKD 2 [n = 14], CKD 3 [n = 17], CKD 4 [n = 12]), in accordance with the current International Renal Interest Society (IRIS) criteria that were used in this study. Blood samples were obtained by jugular venipuncture and urine samples were obtained by cystocentesis. The FEMg was evaluated at a single time point in both urine and blood samples. FEMg was significantly higher in dogs with CKD compared to healthy elderly dogs, especially in advanced stages. This preliminary study demonstrates that FEMg may be altered in dogs with CKD. Further research is warranted to elucidate magnesium's potential role in cardiovascular and arterial calcification in dogs with CKD as observed in humans with CKD.-
Descrição: dc.descriptionVeterinary Teaching Hospital/Animal Science Graduate Program Franca University (UNIFRAN)-
Descrição: dc.descriptionGraduate Program in Veterinary Science (PPGCV)/College of Veterinary Medicine (FAMEV) Federal University of Uberlândia (UFU)-
Descrição: dc.descriptionVeterinary Medicine Graduate Program/School of Veterinary Medicine and Animal Science (FMVZ) Paulista State University (UNESP)-
Descrição: dc.descriptionDepartment of Veterinary Clinic and Surgery Paulista State University (UNESP)-
Descrição: dc.descriptionVeterinary Medicine Graduate Program/School of Veterinary Medicine and Animal Science (FMVZ) Paulista State University (UNESP)-
Descrição: dc.descriptionDepartment of Veterinary Clinic and Surgery Paulista State University (UNESP)-
Idioma: dc.languageen-
Relação: dc.relationTopics in Companion Animal Medicine-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectcanine-
Palavras-chave: dc.subjectkidney-
Palavras-chave: dc.subjectmagnesium homeostasis-
Palavras-chave: dc.subjectnephrology-
Título: dc.titleRenal Magnesium Handling: A Comparison Between Dogs With Chronic Kidney Disease and Healthy Elderly Dogs-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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