Ureasil-Polyether-CoFe2O4Nanocomposites: Coupling a Drug Delivery System and Magnetic Hyperthermia

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorCnrs-
Autor(es): dc.creatorDe Santana, Willian Max O. S.-
Autor(es): dc.creatorAbramson, Sébastien-
Autor(es): dc.creatorFini, Rodolfo-
Autor(es): dc.creatorCaetano, Bruno L.-
Autor(es): dc.creatorMénager, Christine-
Autor(es): dc.creatorPulcinelli, Sandra H.-
Autor(es): dc.creatorSantilli, Celso V.-
Data de aceite: dc.date.accessioned2025-08-21T20:36:10Z-
Data de disponibilização: dc.date.available2025-08-21T20:36:10Z-
Data de envio: dc.date.issued2022-05-01-
Data de envio: dc.date.issued2022-05-01-
Data de envio: dc.date.issued2020-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1021/acsapm.1c00496-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/233613-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/233613-
Descrição: dc.descriptionIn this work, we evaluate the effect of the ureasil-polyether hybrid nature on the magnetic hyperthermia (MH) properties and drug delivery patterns of nanocomposites prepared by the conjugation of cobalt ferrite (CoFe2O4) superparamagnetic nanoparticles (SPN) with ureasil-poly(propylene oxide) (UPPO) and ureasil-poly(ethylene oxide) (UPEO). The results of small-angle X-ray scattering (SAXS) and differential scanning calorimetry (DSC) analyses evidenced that the nanoscopic structure and thermal properties remained essentially unaffected by conjugation of the SPN with the hybrid material. The lower heat capacity of the UPPO-CoFe2O4 nanocomposite promoted a higher efficiency of MH compared to the UPEO-CoFe2O4 nanocomposite. The temperature variations achieved by UPPO-CoFe2O4 and UPEO-CoFe2O4 were 34 and 20 °C, respectively, when subjected to an alternating magnetic field (AMF) for 240 s. The drug delivery patterns of sodium diclofenac (SDCF) from UPPO and UPEO were unaffected by the conjugation with SPN or by MH.-
Descrição: dc.descriptionInstitute of Chemistry São Paulo State University (UNESP), Araraquara-
Descrição: dc.descriptionPhysico-chimie des Electrolytes et Nanosystèmes Interfaciaux Phenix Sorbonne Université Cnrs-
Descrição: dc.descriptionSoft Matter Sciences and Engineering Espci Paris Psl University Sorbonne Université Cnrs-
Descrição: dc.descriptionInstitute of Chemistry São Paulo State University (UNESP), Araraquara-
Idioma: dc.languageen-
Relação: dc.relationACS Applied Polymer Materials-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectcobalt ferrite-
Palavras-chave: dc.subjectmagnetic hyperthermia-
Palavras-chave: dc.subjectnanocomposites-
Palavras-chave: dc.subjectorganic-inorganic hybrid materials-
Palavras-chave: dc.subjectsiloxane-polyether-
Título: dc.titleUreasil-Polyether-CoFe2O4Nanocomposites: Coupling a Drug Delivery System and Magnetic Hyperthermia-
Tipo de arquivo: dc.typelivro digital-
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