3D printed-polylactic acid scaffolds coated with natural rubber latex for biomedical application

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade Federal de São Carlos (UFSCar)-
Autor(es): dc.contributorUniversity of Caxias do Sul (UCS)-
Autor(es): dc.creatorMarcatto, Vinicius Assis-
Autor(es): dc.creatorSant'Ana Pegorin, Giovana-
Autor(es): dc.creatorBarbosa, Gustavo Franco-
Autor(es): dc.creatorHerculano, Rondinelli Donizetti-
Autor(es): dc.creatorGuerra, Nayrim Brizuela-
Data de aceite: dc.date.accessioned2025-08-21T16:09:51Z-
Data de disponibilização: dc.date.available2025-08-21T16:09:51Z-
Data de envio: dc.date.issued2022-05-01-
Data de envio: dc.date.issued2022-05-01-
Data de envio: dc.date.issued2022-03-05-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1002/app.51728-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/233597-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/233597-
Descrição: dc.descriptionThree-dimensional (3D) printing is a rapidly growing technology and plays an emerging role in several biomedical applications. Polylactic acid (PLA) is one of the most common materials in 3D printing, however, it is chemically inert due to the absence of reactive side chain groups. In this context, in this work, the PLA scaffolds with two different geometries were produced and coated with natural rubber latex (NRL) extracted from the rubber tree Hevea brasiliensis. NRL presents bioactive substances that are related to its biological properties. The results revealed scaffolds with interconnected pores and pores sizes from 600 to 1300 μm. The NRL coatings caused a decrease in pore size. Infrared spectra showed that 2 NRL layers were more efficient in coverage. Compressive strength values obtained are in agreement with the spongy bones value (22–24 MPa for crossbar and 20–22 MPa for roundbar cube). Finally, the hemolytic activity of the PLA scaffold was 3%, while the scaffolds coated with 1 and 2 NRL layers presented values of 0%, indicating a potential use in biomedical applications due to the absence of hemolytic effects.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionBiomaterials and Bioprocess Engineering Postgraduate Program São Paulo State University (UNESP) School of Pharmaceutical Sciences-
Descrição: dc.descriptionSão Paulo State University (UNESP) Institute of Chemistry-
Descrição: dc.descriptionMechanical Engineering Department Federal University of São Carlos (UFSCar)-
Descrição: dc.descriptionBiotechnology and Bioprocess Engineering Department São Paulo State University (UNESP) School of Pharmaceutical Sciences-
Descrição: dc.descriptionArea of Exact Sciences and Engineering University of Caxias do Sul (UCS)-
Descrição: dc.descriptionBiomaterials and Bioprocess Engineering Postgraduate Program São Paulo State University (UNESP) School of Pharmaceutical Sciences-
Descrição: dc.descriptionSão Paulo State University (UNESP) Institute of Chemistry-
Descrição: dc.descriptionBiotechnology and Bioprocess Engineering Department São Paulo State University (UNESP) School of Pharmaceutical Sciences-
Descrição: dc.descriptionFAPESP: 2011/17411-8-
Descrição: dc.descriptionFAPESP: 2014/17526-8-
Descrição: dc.descriptionFAPESP: 2017/19603-8-
Descrição: dc.descriptionCNPq: 314516/2018-2-
Idioma: dc.languageen-
Relação: dc.relationJournal of Applied Polymer Science-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectbiocompatibility-
Palavras-chave: dc.subjectbiomaterials-
Palavras-chave: dc.subjectbiomedical applications-
Palavras-chave: dc.subjectmanufacturing-
Palavras-chave: dc.subjectrubber-
Título: dc.title3D printed-polylactic acid scaffolds coated with natural rubber latex for biomedical application-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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