Assessment of force production in parkinson’s disease subtypes

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversity of Otago-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorWeizmann Institute of Science-
Autor(es): dc.creatorPelicioni, Paulo Henrique Silva-
Autor(es): dc.creatorPereira, Marcelo Pinto-
Autor(es): dc.creatorLahr, Juliana-
Autor(es): dc.creatorDos Santos, Paulo Cezar Rocha-
Autor(es): dc.creatorGobbi, Lilian Teresa Bucken-
Data de aceite: dc.date.accessioned2025-08-21T21:49:58Z-
Data de disponibilização: dc.date.available2025-08-21T21:49:58Z-
Data de envio: dc.date.issued2022-05-01-
Data de envio: dc.date.issued2022-05-01-
Data de envio: dc.date.issued2021-10-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/ijerph181910044-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/233571-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/233571-
Descrição: dc.descriptionMuscle weakness is a secondary motor symptom of Parkinson’s disease (PD), especially in the subtype characterized by postural instability and gait difficulty (PIGD). Since the PIGD subtype also presents worse bradykinesia, we hypothesized that it also shows a decreased rate of force development, which is linked to an increased risk of falling in PD. Therefore, we investigated the effects of PD and PD subtypes on a force production profile and correlated the force production outcomes with clinical symptoms for each PD subtype. We assessed three groups of participants: 14 healthy older adults (OA), 10 people with PD composing the PIGD group, and 14 people with PD composing the tremor-dominant group. Three knee extension maximum voluntary isometric contractions were performed in a leg extension machine equipped with a load cell to assess the force production. The outcome measures were: peak force and rate of force development (RFD) at 50 ms (RFD50), 100 ms (RFD100), and 200 ms (RFD200). We observed lower peak force, RFD50, RFD100, and RFD200 in people with PD, regardless of subtypes, compared with the OA group (p < 0.05 for all comparisons). Together, our results indicated that PD affects the capacity to produce maximal and rapid force. Therefore, future interventions should consider rehabilitation programs for people with PD based on muscle power and fast-force production, and consequently reduce the likelihood of people with PD falling from balance-related events, such as from an unsuccessful attempt to avoid a tripping hazard or a poor and slower stepping response.-
Descrição: dc.descriptionSchool of Physiotherapy Division of Health Sciences University of Otago-
Descrição: dc.descriptionPosture and Locomotion Studies Laboratory Universidade Estadual Paulista (UNESP)-
Descrição: dc.descriptionDepartment of Computer Science and Applied Mathematics Weizmann Institute of Science-
Descrição: dc.descriptionPosture and Locomotion Studies Laboratory Universidade Estadual Paulista (UNESP)-
Idioma: dc.languageen-
Relação: dc.relationInternational Journal of Environmental Research and Public Health-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectForce production-
Palavras-chave: dc.subjectMuscle power-
Palavras-chave: dc.subjectParkinson’s disease-
Palavras-chave: dc.subjectSubtypes-
Título: dc.titleAssessment of force production in parkinson’s disease subtypes-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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