Naturally enriched 13C breath test as a carbohydrate intake marker in obese women

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversity of Wisconsin-
Autor(es): dc.creatorBeato, Gabriel Cunha-
Autor(es): dc.creatorRavelli, Michele Novaes-
Autor(es): dc.creatorSartori, Maria Márcia Pereira-
Autor(es): dc.creatorde Oliveira, Maria Rita Marques-
Data de aceite: dc.date.accessioned2025-08-21T18:24:04Z-
Data de disponibilização: dc.date.available2025-08-21T18:24:04Z-
Data de envio: dc.date.issued2022-05-01-
Data de envio: dc.date.issued2022-05-01-
Data de envio: dc.date.issued2020-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1186/s41110-020-00119-z-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/233475-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/233475-
Descrição: dc.descriptionBackground: The 13C breath test has been proposed as a potential biomarker for the evaluation of metabolism and carbohydrate intake. To study the dynamics of the use of substrates in human metabolism is especially important for glucose metabolism in obese people. Purpose: This study aimed to verify the use of 13C in a naturally enriched corn glucose liquid meal through the breath test as a potential marker of energy metabolism in women with a body mass index (BMI) above 35 kg /m2. Methods: Twenty-five woman (13 non-obese; 12 obese) participated in the study. The breath samples were collected in tubes prior to consumption of the standard liquid meal and at 30-min intervals for 6 h and analyzed in a continuous flow isotope ratio mass spectrometer. The curves of breath isotopic enrichment were adjusted by the Boltzmann sigmoidal regression model, and the t test was used to evaluate differences between the means of the curves. Results: It was found a faster metabolic turn-over of the 13C-glucose in obese women. Conclusion: The breath test using naturally enriched stable isotopes has potential to be used as an energy metabolism marker in subjects with different BMI.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionSchool of Pharmaceutical Sciences São Paulo State University (UNESP), Araraquara-Jaú Road, km 01, s/n-
Descrição: dc.descriptionDepartment of Neurology University of Wisconsin, 1685 Highland Avenue, Medical Foundation Centennial Building, 7th Floor-
Descrição: dc.descriptionSchool of Agronomic Sciences São Paulo State University (UNESP), Lageado Experimental Farm, s/n-
Descrição: dc.descriptionInstitute of Biosciences São Paulo State University (UNESP), Antônio Celso Wagner Zanin, 250-
Descrição: dc.descriptionSchool of Pharmaceutical Sciences São Paulo State University (UNESP), Araraquara-Jaú Road, km 01, s/n-
Descrição: dc.descriptionSchool of Agronomic Sciences São Paulo State University (UNESP), Lageado Experimental Farm, s/n-
Descrição: dc.descriptionInstitute of Biosciences São Paulo State University (UNESP), Antônio Celso Wagner Zanin, 250-
Descrição: dc.descriptionFAPESP: 2013/05358-0-
Idioma: dc.languageen-
Relação: dc.relationNutrire-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subject13C-glucose-
Palavras-chave: dc.subjectBiomarker-
Palavras-chave: dc.subjectBreath test-
Palavras-chave: dc.subjectGlucose metabolism-
Palavras-chave: dc.subjectStable isotopes-
Título: dc.titleNaturally enriched 13C breath test as a carbohydrate intake marker in obese women-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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