Ex vivo study of use of physiotherapy ultrasound in polymethylmethacrylate beads doped with methylene blue as an antibiotic carrier

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.creatorMaciel, Luigi Milanez Ávila Dias-
Autor(es): dc.creatorRahal, Sheila Canevese-
Autor(es): dc.creatorMelchert, Alessandra-
Autor(es): dc.creatorFilho, Tulio Genari-
Autor(es): dc.creatorMaciel, Carlos Dias-
Autor(es): dc.creatorDos Santos, Ivan Felismino Charas-
Data de aceite: dc.date.accessioned2025-08-21T21:04:40Z-
Data de disponibilização: dc.date.available2025-08-21T21:04:40Z-
Data de envio: dc.date.issued2022-05-01-
Data de envio: dc.date.issued2022-05-01-
Data de envio: dc.date.issued2020-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1590/1809-6891V22E-68013-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/233459-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/233459-
Descrição: dc.descriptionPolymethylmethacrylate bone cement is a standard material used as antibiotic carrier in the orthopedic surgery. The ultrasonic energy method is capable of triggering biological effects based on both thermal and non-thermal mechanisms. The aim of the current study is to analyze methylene blue dispersion in polymethylmethacrylate beads, in association with the acoustic field generated by non-thermal ultrasound. Forty-nine specimens were used, and each specimen comprised one polymethylmethacrylate bead (0.6-mm diameter) doped with methylene blue and deposited in gelatin sample. Forty test specimens were divided into four groups comprising 10 samples, each, based on different ultrasound intensities (Group 1: 1.0 W/cm2; Group 2: 1.5 W/ cm2) and polymethylmethacrylate bead depths (A - 2 cm; B - 3 cm) in gelatin sample. The control group comprised other nine specimens and statistically differed from the other groups. All groups irradiated with ultrasound have shown statistically significant differences in methylene blue dispersion, except for Groups 2A and 2B. Methylene blue dispersion in gelatin among groups was 1A> 1B; 2A> 1A; 2B> 1A; 2A> 1B; and 2B> 1B. Low-intensity ultrasound enabled the highest methylene blue dispersion when polymethylmethacrylate bead was positioned superficial; bead depth associated with high-intensity ultrasound did not influence methylene blue dispersion.-
Descrição: dc.descriptionUniversidade Estadual Paulista (UNESP), SP-
Descrição: dc.descriptionUniversidade de São Paulo (USP), SP-
Descrição: dc.descriptionUniversidade Estadual Paulista (UNESP), SP-
Idioma: dc.languageen-
Relação: dc.relationCiencia Animal Brasileira-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectNon-thermal ultrasound-
Palavras-chave: dc.subjectOsteomyelitis-
Palavras-chave: dc.subjectPhonophoresis-
Palavras-chave: dc.subjectTreatment-
Título: dc.titleEx vivo study of use of physiotherapy ultrasound in polymethylmethacrylate beads doped with methylene blue as an antibiotic carrier-
Título: dc.titleEstudo ex vivo do uso do ultrassom fisioterapêutico em pérolas de polimetilmetacrilato dopadas com azul de metileno como carreador de antibiótico-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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