Paramyxoviruses from neotropical bats suggest a novel genus and nephrotropism

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversity of Texas Medical Branch-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorUniversity of Oxford-
Autor(es): dc.contributorGorgas Memorial Institute of Health Studies-
Autor(es): dc.contributorEvandro Chagas Institute-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorImperial College London-
Autor(es): dc.contributorMRC-University of Glasgow Centre for Virus Research-
Autor(es): dc.creatorde Souza, William Marciel-
Autor(es): dc.creatorFumagalli, Marcilio Jorge-
Autor(es): dc.creatorCarrera, Jean Paul-
Autor(es): dc.creatorde Araujo, Jansen-
Autor(es): dc.creatorCardoso, Jedson Ferreira-
Autor(es): dc.creatorde Carvalho, Cristiano-
Autor(es): dc.creatorDurigon, Edison Luiz-
Autor(es): dc.creatorQueiroz, Luzia Helena-
Autor(es): dc.creatorFaria, Nuno Rodrigues-
Autor(es): dc.creatorMurcia, Pablo R.-
Autor(es): dc.creatorFigueiredo, Luiz Tadeu Moraes-
Data de aceite: dc.date.accessioned2025-08-21T22:50:53Z-
Data de disponibilização: dc.date.available2025-08-21T22:50:53Z-
Data de envio: dc.date.issued2022-05-01-
Data de envio: dc.date.issued2022-05-01-
Data de envio: dc.date.issued2021-10-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.meegid.2021.105041-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/233426-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/233426-
Descrição: dc.descriptionParamyxoviruses have a broad host range and geographic distribution, including human pathogens transmitted by bats, such as Nipah and Hendra viruses. In this study, we combined high-throughput sequencing and molecular approaches to investigate the presence of paramyxoviruses in neotropical bats (Microchiroptera suborder) in Brazil. We discovered and characterized three novel paramyxoviruses in the kidney tissues of apparently healthy common vampire bats (D. rotundus) and Seba's short-tailed bats (C. perspicillata), which we tentatively named Kanhgág virus (KANV), Boe virus (BOEV), and Guató virus (GUATV). In this study, we classified these viruses as putative species into the Macrojêvirus genus, a newly proposed genus of the Orthoparamyxovirinae subfamily. Using RT-PCR, we detected these viruses in 20.9% (9 out of 43) of bats tested, and viral RNA was detected exclusively in kidney tissues. Attempts to isolate infectious virus were successful for KANV and GUATV. Our results expand the viral diversity, host range, and geographical distribution of the paramyxoviruses.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionMedical Research Council-
Descrição: dc.descriptionNational Institutes of Health-
Descrição: dc.descriptionWorld Reference Center for Emerging Viruses and Arboviruses and Department of Microbiology and Immunology University of Texas Medical Branch-
Descrição: dc.descriptionVirology Research Center Ribeirão Preto Medical School University of São Paulo, Ribeirão Preto-
Descrição: dc.descriptionDepartment of Zoology University of Oxford-
Descrição: dc.descriptionDepartment of Research in Virology and Biotechnology Gorgas Memorial Institute of Health Studies-
Descrição: dc.descriptionInstitute of Biomedical Sciences University of São Paulo-
Descrição: dc.descriptionEvandro Chagas Institute, Ministry of Health-
Descrição: dc.descriptionFaculty of Veterinary Medicine São Paulo State University, Araçatuba-
Descrição: dc.descriptionDepartment of Infectious Disease Epidemiology Imperial College London-
Descrição: dc.descriptionMRC-University of Glasgow Centre for Virus Research-
Descrição: dc.descriptionFaculty of Veterinary Medicine São Paulo State University, Araçatuba-
Descrição: dc.descriptionFAPESP: 06/00572-0-
Descrição: dc.descriptionFAPESP: 13/14929-1-
Descrição: dc.descriptionFAPESP: 15/05778-5-
Descrição: dc.descriptionFAPESP: 17/13981-0-
Descrição: dc.descriptionFAPESP: 18/09383-3-
Descrição: dc.descriptionFAPESP: 18/14389-0-
Descrição: dc.descriptionFAPESP: 19/24251-9-
Descrição: dc.descriptionMedical Research Council: MC_UU_12014/9-
Descrição: dc.descriptionNational Institutes of Health: R24 AI120942-
Idioma: dc.languageen-
Relação: dc.relationInfection, Genetics and Evolution-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBat-borne diseases-
Palavras-chave: dc.subjectParamyxoviridae-
Palavras-chave: dc.subjectParamyxovirus-
Palavras-chave: dc.subjectVirus discovery-
Título: dc.titleParamyxoviruses from neotropical bats suggest a novel genus and nephrotropism-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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