New insights into physicochemical aspects involved in the formation of polyelectrolyte complexes based on chitosan and dextran sulfate

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.creatorCarvalho, Suzana Gonçalves-
Autor(es): dc.creatordos Santos, Aline Martins-
Autor(es): dc.creatorSilvestre, Amanda Letícia Polli-
Autor(es): dc.creatorMeneguin, Andréia Bagliotti-
Autor(es): dc.creatorFerreira, Leonardo Miziara Barboza-
Autor(es): dc.creatorChorilli, Marlus-
Autor(es): dc.creatorGremião, Maria Palmira Daflon-
Data de aceite: dc.date.accessioned2025-08-21T15:19:27Z-
Data de disponibilização: dc.date.available2025-08-21T15:19:27Z-
Data de envio: dc.date.issued2022-05-01-
Data de envio: dc.date.issued2022-05-01-
Data de envio: dc.date.issued2021-10-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.carbpol.2021.118436-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/233269-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/233269-
Descrição: dc.descriptionPolyelectrolyte complexation is a technique based on interactions between polyelectrolytes of opposite charges driven by supramolecular interactions. Although many studies address the formation of polyelectrolyte complexes (PECs), few explore strategies and tools to select the best working conditions and are often based on empirical choices. This study evaluates the influence of pH, molecular weight, and polymeric proportion on the formation of PECs based on chitosan:dextran sulfate. In addition, it assesses the approaches that study the influence of pH on the zeta potential of polymeric dispersions as a tool in the design of PECs. Results showed that nanoparticles with an excess of polycation formed aggregates, while an excess of dextran sulfate reduced the size of the particles. The graph of zeta potential as a function of pH proved to be a promising tool in the choice of polymers and a better pH condition in the development of PECs.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionUniversidade Estadual Paulista-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionDepartment of Drugs and Pharmaceutics School of Pharmaceutical Sciences São Paulo State University (UNESP)-
Descrição: dc.descriptionNanomedicine and Nanotoxicology Group (GNANO) University of São Paulo (USP)-
Descrição: dc.descriptionDepartment of Drugs and Pharmaceutics School of Pharmaceutical Sciences São Paulo State University (UNESP)-
Descrição: dc.descriptionFAPESP: 2019/10761-5-
Idioma: dc.languageen-
Relação: dc.relationCarbohydrate Polymers-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectChitosan-
Palavras-chave: dc.subjectChitosan oligosaccharide-
Palavras-chave: dc.subjectDextran sulfate-
Palavras-chave: dc.subjectMolecular weight-
Palavras-chave: dc.subjectNanoparticles-
Palavras-chave: dc.subjectPolyelectrolyte complexation-
Título: dc.titleNew insights into physicochemical aspects involved in the formation of polyelectrolyte complexes based on chitosan and dextran sulfate-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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