Design of experiments (DoE) to develop and to optimize nanoparticles as drug delivery systems

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorUniversidade Federal de Minas Gerais (UFMG)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorTavares Luiz, Marcela-
Autor(es): dc.creatorSantos Rosa Viegas, Juliana-
Autor(es): dc.creatorPalma Abriata, Juliana-
Autor(es): dc.creatorViegas, Felipe-
Autor(es): dc.creatorTesta Moura de Carvalho Vicentini, Fabiana-
Autor(es): dc.creatorLopes Badra Bentley, Maria Vitória-
Autor(es): dc.creatorChorilli, Marlus-
Autor(es): dc.creatorMaldonado Marchetti, Juliana-
Autor(es): dc.creatorTapia-Blácido, Delia Rita-
Data de aceite: dc.date.accessioned2025-08-21T16:42:58Z-
Data de disponibilização: dc.date.available2025-08-21T16:42:58Z-
Data de envio: dc.date.issued2022-05-01-
Data de envio: dc.date.issued2022-05-01-
Data de envio: dc.date.issued2021-08-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.ejpb.2021.05.011-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/233175-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/233175-
Descrição: dc.descriptionNanotechnology has been widely applied to develop drug delivery systems to improve therapeutic performance. The effectiveness of these systems is intrinsically related to their physicochemical properties, so their biological responses are highly susceptible to factors such as the type and quantity of each material that is employed in their synthesis and to the method that is used to produce them. In this context, quality-oriented manufacturing of nanoparticles has been an important strategy to understand and to optimize the factors involved in their production. For this purpose, Design of Experiment (DoE) tools have been applied to obtain enough knowledge about the process and hence achieve high-quality products. This review aims to set up the bases to implement DoE as a strategy to improve the manufacture of nanocarriers and to discuss the main factors involved in the production of the most common nanocarriers employed in the pharmaceutical field.-
Descrição: dc.descriptionSchool of Pharmaceutical Sciences of Ribeirao Preto University of Sao Paulo-
Descrição: dc.descriptionDepartment of Computer Science Federal University of Minas Gerais, Belo Horizonte-
Descrição: dc.descriptionSchool of Pharmaceutical Sciences Sao Paulo State University-
Descrição: dc.descriptionDepartment of Chemistry Faculty of Philosophy Sciences and Letters of Ribeirao Preto University of São Paulo-
Descrição: dc.descriptionSchool of Pharmaceutical Sciences Sao Paulo State University-
Formato: dc.format127-148-
Idioma: dc.languageen-
Relação: dc.relationEuropean Journal of Pharmaceutics and Biopharmaceutics-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBox-Behnken Design-
Palavras-chave: dc.subjectCentral Composite Design-
Palavras-chave: dc.subjectFractional Factorial Design-
Palavras-chave: dc.subjectFull Factorial Design-
Palavras-chave: dc.subjectNanomedicine-
Palavras-chave: dc.subjectNanotechnology-
Palavras-chave: dc.subjectPlackett-Burman Design-
Palavras-chave: dc.subjectQuality by Design-
Palavras-chave: dc.subjectResponse Surface Methodology-
Título: dc.titleDesign of experiments (DoE) to develop and to optimize nanoparticles as drug delivery systems-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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