Mouthwashes: An in vitro study of their action on microbial biofilms and cytotoxicity to gingival fibroblasts

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorDe Oliveira, Jonatas Rafael-
Autor(es): dc.creatorBelato, Kely Karina-
Autor(es): dc.creatorDe Oliveira, Felipe Eduardo-
Autor(es): dc.creatorJorge, Antonio Olavo Cardoso-
Autor(es): dc.creatorCamargo, Samira Esteves Afonso-
Autor(es): dc.creatorDe Oliveira, Luciane Dias-
Data de aceite: dc.date.accessioned2025-08-21T19:39:31Z-
Data de disponibilização: dc.date.available2025-08-21T19:39:31Z-
Data de envio: dc.date.issued2022-04-30-
Data de envio: dc.date.issued2022-04-30-
Data de envio: dc.date.issued2018-03-01-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/232754-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/232754-
Descrição: dc.descriptionThis study evaluated the in vitro antibiofilm effect of 5 different commercial mouthwashes (Cepacol Traditional, Colgate Plax Fresh Mint, Listerine Cool Mint, Oral-B Complete, and Sensodyne) on Candida albicans, Staphylococcus aureus, Enterococcus faecalis, Streptococcus mutans, Escherichia coli, and Pseudomonas aeruginosa. The cytotoxic effect of the mouthwashes on gingival fibroblasts was also analyzed. A colorimetric assay with 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) was used to investigate the viability of biofilms after 48 hours and gingival fibroblasts after 24 hours. The biofilms were exposed to the mouthwashes for 2 different lengths of time: T1, the time recommended by the manufacturer (30 or 60 seconds); and T2, double the recommended time (60 or 120 seconds). All antiseptic mouthwashes caused a significant reduction of biofilm (P < 0.05) as well as a significant reduction of viable gingival fibroblasts (P < 0.05) with both exposure times (T1 and T2). It can be concluded that the commercial mouthwashes demonstrated effective antibiofilm activity; they were more effective on bacteria than on C albicans. A significant cytotoxic effect on gingival fibroblasts was also observed.-
Descrição: dc.descriptionDepartment of Biosciences and Oral Diagnosis São Paulo State University Institute of Science and Technology-
Descrição: dc.descriptionDepartment of Biosciences and Oral Diagnosis São Paulo State University Institute of Science and Technology-
Formato: dc.format28-34-
Idioma: dc.languageen-
Relação: dc.relationGeneral Dentistry-
???dc.source???: dc.sourceScopus-
Título: dc.titleMouthwashes: An in vitro study of their action on microbial biofilms and cytotoxicity to gingival fibroblasts-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.