Femoral biomechanic and microtomography from male rats submitted to dietary restriction supplemented with sucrose

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorAraçatuba Dental School-
Autor(es): dc.contributorUniversidade Federal de São Carlos (UFSCar)-
Autor(es): dc.contributorMedicine Veterinarian School at Araçatuba-
Autor(es): dc.creatorCarvalho, A. A.F.-
Autor(es): dc.creatorBiffe, B. G.-
Autor(es): dc.creatorNakamune, Ana Cláudia de Melo Stevanato-
Autor(es): dc.creatorLouzada, M. J.Q.-
Data de aceite: dc.date.accessioned2025-08-21T17:49:48Z-
Data de disponibilização: dc.date.available2025-08-21T17:49:48Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2013-10-23-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/231306-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/231306-
Descrição: dc.descriptionFood restriction reduces body weight and influence bone mass and also is correlated with bone mineral density (BMD). Mechanisms have been proposed for the loss of BMD after body weight reduction, including reduced energy intake. Growing 8 wk-old Wistar male rats were randomly divided into Control and Calorie restriction associated with sucrose 30% (CRS). These animals were subjected to intermittent food restriction during 8 weeks and had free access to tap water and sucrose30% in distilled water. The rats were euthanized at the end of week 8, blood collected from abdominal aorta artery, femurs cleaned of adherent soft tissues, scanned using dual energy X-ray absorptiometry, structural and material properties determined by three-point bending testing in the mid-diaphyseal region, bone surface tested in a microhardness tester and microstructure was assessed in a microcomputer tomography. In CRS animals body weight decreased significantly relative to the Control animals. There was a clear option for high-sucrose beverage in CRS animals. No difference was observed in biochemical, densitometric and biomechanical analyzes. Results from micro CT showed only significant difference in connectivity of trabecular bone. It has been suggested that rats submitted to food restriction consumed sugar not because of its inherent palatability, but in order to alter their macronutrient balance and animals need to meet energy demands in high-sucrose.-
Descrição: dc.descriptionDepartment of Pathology Araçatuba Dental School, CEP 16015-050, Araçatuba, SP-
Descrição: dc.descriptionDepartment of Physiology Sciences Federal University of São Carlos - UFSCar, São Carlos, SP-
Descrição: dc.descriptionDepartment of Basic Sciences Araçatuba Dental School, CEP 16015-050, Araçatuba, SP-
Descrição: dc.descriptionDepartment of Support, Production and Animal Health Medicine Veterinarian School at Araçatuba, CEP 16015-050, Araçatuba, SP-
Formato: dc.format176-181-
Idioma: dc.languageen-
Relação: dc.relationJournal of Morphological Sciences-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBone mineral density-
Palavras-chave: dc.subjectFemoral biomechanics-
Palavras-chave: dc.subjectFemoral microtomography-
Palavras-chave: dc.subjectFood restriction-
Título: dc.titleFemoral biomechanic and microtomography from male rats submitted to dietary restriction supplemented with sucrose-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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