Myeloperoxidase as inflammatory marker of periodontal disease: Experimental study in rats

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorEducational Foundation of Barretos-
Autor(es): dc.creatorGomes, Dbora A. S.-
Autor(es): dc.creatorPires, Juliana R.-
Autor(es): dc.creatorZuza, Elizangela P.-
Autor(es): dc.creatorMuscara, Marcelo N.-
Autor(es): dc.creatorHerrera, Bruno S.-
Autor(es): dc.creatorSpolidorio, Lus C.-
Autor(es): dc.creatorToledo, Benedicto E. C.-
Autor(es): dc.creatorSpolidorio, Denise M. P.-
Data de aceite: dc.date.accessioned2025-08-21T21:00:17Z-
Data de disponibilização: dc.date.available2025-08-21T21:00:17Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2009-11-09-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1080/08820130802457503-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/231198-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/231198-
Descrição: dc.descriptionRationale: Previous studies have used myeloperoxidase (MPO) as an inflammatory marker to estimate the accumulation of neutrophils in inflamed regions. Objective: The aim of this experimental study was to quantify the levels of MPO related to experimental periodontal disease in rats. Methods: Periodontal disease was induced in a group of rats using placement of a ligature around molar teeth. A group of rats without ligature placement served as a control. Measurements were made on the 3rd, 7th, 15 th and 30th day from baseline. Gingival tissues were taken for quantification of MPO levels by ELISA. Results: The rats with induced periodontal disease showed statistically higher MPO levels (p < 0.05) when compared to control rats. A significant increase in the levels of MPO released on days 7 and 30 was observed, with higher levels in the group with induced periodontitis. Conclusion: The levels of MPO were found to be higher in rats with induced periodontal disease, confirming the hypothesis that MPO may serve as an inflammatory marker for periodontitis.-
Descrição: dc.descriptionDepartment of Diagnosis and Oral Surgery State University of São Paulo, Araraquara, São Paulo-
Descrição: dc.descriptionDepartment of Periodontics Educational Foundation of Barretos, Barretos, São Paulo-
Descrição: dc.descriptionDepartment of Pathology State University of São Paulo, Araraquara, São Paulo-
Descrição: dc.descriptionDepartment of Pharmacology University of São Paulo (USP), São Paulo-
Formato: dc.format117-122-
Idioma: dc.languageen-
Relação: dc.relationImmunological Investigations-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectEnzymes-
Palavras-chave: dc.subjectInflammation-
Palavras-chave: dc.subjectPeriodontal diseases-
Palavras-chave: dc.subjectPeroxidase-
Título: dc.titleMyeloperoxidase as inflammatory marker of periodontal disease: Experimental study in rats-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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