Genetics of acheiropodia (the handless and footless families of Brazil). VII. Population dynamics

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.creatorFreire Maia, A.-
Autor(es): dc.creatorLi, W. H.-
Autor(es): dc.creatorMaruyama, T.-
Data de aceite: dc.date.accessioned2025-08-21T17:25:50Z-
Data de disponibilização: dc.date.available2025-08-21T17:25:50Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued1975-12-01-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/230778-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/230778-
Descrição: dc.descriptionSince carriers of the acheiropodia gene cannot be distinguished from noncarriers, parents and normal sibs of affected individuals have been used to estimate the fitness of heterozygotes. No significant difference in biologic fitness (viability and fertility) between normal sibs and the general population could be detected. A comparison between acheiropods nonsignificant their normal sibs showed the following: (1) a significant difference in stillbirth rate; (2) a higher mortality rate of acheiropids in the first 5 years of life; (3) a relative viability not larger than .7; (4) a relative fertility no greater than .14, due to 'cosmetic effects'; and (5) a fitness of .10 or lower. The lower number of acheiropodia genes in Brazil has been calculated as 25,000 in the 1970s. The data are compatible with an extremely low mutation rate and a very stable locus. It is suggested that all Brazilian acheiropods can be traced to a single mutation. A conservative estimate of the number of acheiropods to appear in the future in Brazil is 14,000 with an extinction time of no less than 2,300 generations or almost 70,000 years. A variety of other parameters have been calculated.-
Descrição: dc.descriptionDept. Genet., Fac. Ci. Med. Biol., Botucatu-
Formato: dc.format665-675-
Idioma: dc.languageen-
Relação: dc.relationAmerican Journal of Human Genetics-
???dc.source???: dc.sourceScopus-
Título: dc.titleGenetics of acheiropodia (the handless and footless families of Brazil). VII. Population dynamics-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.