THE ROUND LIGAMENT IN DEVELOPMENTAL HIP DYSPLASIA: ARE ITS MECHANICAL AND HISTOLOGICAL PROPERTIES PRESERVED?

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorAssociação de Assistência à Criança Deficiente (AACD)-
Autor(es): dc.creatorZuccon, Alexandre-
Autor(es): dc.creatorPereira, Hamilton Da Rosa-
Autor(es): dc.creatorSantos, Sérgio Alexandre Alcântara Dos-
Autor(es): dc.creatorFelisbino, Sérgio Luís-
Autor(es): dc.creatorJunior, Luís Antônio Justulin-
Autor(es): dc.creatorCataneo, Daniele Cristina-
Data de aceite: dc.date.accessioned2025-08-21T15:34:12Z-
Data de disponibilização: dc.date.available2025-08-21T15:34:12Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2021-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1590/1413-785220223001e235808-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/230572-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/230572-
Descrição: dc.descriptionIntroduction: During open surgical dislocated hip reduction, several anatomical structures, such as the round ligament, are approached. However, there is controversy over both the possibility of preserving the ligament and its functional importance. Materials and Methods: This experimental study used skeletally immature rabbits as a model for congenital hip dislocation. Thirty-six rabbits comprised the sample that was submitted to the round ligament analysis. The sample was stratified for analysis (biomechanics, zymography, histology, and immunohistochemistry). Statistical analysis compared the unstable side to the control side of each rabbit. Results: Biomechanical assays showed that the mean maximal strength of the round ligament on the unstable side was similar to that of the control side (p = 0.594), which was also the case with maximum deformation (p = 0.328). Histologically, there was a statistically significant increase in cellularity on the unstable side (p <0.001). Additionally, there was significantly greater collagen occupancy on the control side (p <0.001). Zymography revealed no significant difference in the amount of active metalloproteinase 2 (MMP-2) (p = 0.068). Conclusions: Although histological analysis found evidence of significant changes in the RL in unstable hips, there were no significant differences in zymography, and no changes were observed in biomechanical tests. Evidence Level V; Experimental study.-
Descrição: dc.descriptionUniversidade Estadual Paulista (UNESP) Faculdade de Medicina de Botucatu Department of Surgery and Orthopedics, SP-
Descrição: dc.descriptionAssociação de Assistência à Criança Deficiente (AACD) Department of Orthopedics, SP-
Descrição: dc.descriptionUniversidade Estadual Paulista (UNESP) Instituto de Biociências de Botucatu Department of Structural and Functional Biology, SP-
Descrição: dc.descriptionUniversidade Estadual Paulista (UNESP) Faculdade de Medicina de Botucatu Department of Surgery and Orthopedics, SP-
Descrição: dc.descriptionUniversidade Estadual Paulista (UNESP) Instituto de Biociências de Botucatu Department of Structural and Functional Biology, SP-
Formato: dc.format1-6-
Idioma: dc.languageen-
Idioma: dc.languagept_BR-
Relação: dc.relationActa Ortopedica Brasileira-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectanimal-
Palavras-chave: dc.subjectCoelhos-
Palavras-chave: dc.subjectCollagen-
Palavras-chave: dc.subjectColágeno-
Palavras-chave: dc.subjectHip dislocation-
Palavras-chave: dc.subjectLigamentos redondos-
Palavras-chave: dc.subjectLuxação do quadril-
Palavras-chave: dc.subjectModelos animais-
Palavras-chave: dc.subjectModels-
Palavras-chave: dc.subjectRabbits-
Palavras-chave: dc.subjectRound ligaments-
Título: dc.titleTHE ROUND LIGAMENT IN DEVELOPMENTAL HIP DYSPLASIA: ARE ITS MECHANICAL AND HISTOLOGICAL PROPERTIES PRESERVED?-
Título: dc.titleO LIGAMENTO REDONDO NA DISPLASIA DO DESENVOLVIMENTO DO QUADRIL: SUAS PROPRIEDADES MECÂNICAS E HISTOLÓGICAS SÃO PRESERVADAS?-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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