Hospitalization costs of coronaviruses diseases in upper-middle-income countries: A systematic review

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Autor(es): dc.contributorUniversidade Federal de São Paulo (UNIFESP)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorHospital Alemão Oswaldo Cruz-
Autor(es): dc.contributorUniversidade de Santo Amaro-
Autor(es): dc.contributorUniversidade Federal do Amapá-
Autor(es): dc.contributorBeneficência Portuguesa de São Paulo-
Autor(es): dc.creatorRocha-Filho, César Ramos-
Autor(es): dc.creatorMartins, Johnny Wallef Leite-
Autor(es): dc.creatorLucchetta, Rosa Camila-
Autor(es): dc.creatorRamalho, Gabriel Sodré-
Autor(es): dc.creatorTrevisani, Giulia Fernandes Moça-
Autor(es): dc.creatorda Rocha, Aline Pereira-
Autor(es): dc.creatorPinto, Ana Carolina Pereira Nunes-
Autor(es): dc.creatorde Assis Reis, Felipe Sebastião-
Autor(es): dc.creatorFerla, Laura Jantsch-
Autor(es): dc.creatorde Carvalho Mastroianni, Patrícia-
Autor(es): dc.creatorCorrea, Luci-
Autor(es): dc.creatorSaconato, Humberto-
Autor(es): dc.creatorTrevisani, Virgínia Fernandes Moça-
Data de aceite: dc.date.accessioned2025-08-21T15:26:57Z-
Data de disponibilização: dc.date.available2025-08-21T15:26:57Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-03-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1371/journal.pone.0265003-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/230570-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/230570-
Descrição: dc.descriptionBackground COVID-19, SARS and MERS are diseases that present an important health burden worldwide. This situation demands resource allocation to the healthcare system, affecting especially middle- and low-income countries. Thus, identifying the main cost drivers is relevant to optimize patient care and resource allocation. Objective To systematically identify and summarize the current status of knowledge on direct medical hospitalization costs of SARS, MERS, or COVID-19 in Upper-Middle-Income Countries. Methods We conducted a systematic review across seven key databases (PubMed, EMBASE, BVS Portal, CINAHL, CRD library, MedRxiv and Research Square) from database inception to February 2021. Costs extracted were converted into 2021 International Dollars using the Purchasing Power Parity-adjusted. The assessment of quality was based on the protocol by the BMJ and CHEERS. PROSPERO 2020: CRD42020225757. Results No eligible study about SARS or MERS was recovered. For COVID-19, five studies presented cost analysis performed in Brazil, China, Iran, and Turkey. Regarding total direct medical costs, the lowest cost per patient at ward was observed in Turkey ($900.08), while the highest in Brazil ($5,093.38). At ICU, the lowest was in Turkey ($2,984.78), while the highest was in China ($52,432.87). Service care was the most expressive (58% to 88%) cost driver of COVID-19 patients at ward. At ICU, there was no consensus between service care (54% to 87%) and treatment (72% to 81%) as key burdens of total cost. Conclusion Our findings elucidate the importance of COVID-19 on health-economic outcomes. The marked heterogeneity among studies leaded to substantially different results and made challenging the comparison of data to estimate pooled results for single countries or regions. Further studies concerning cost estimates from standardized analysis may provide clearer data for a more substantial analysis. This may help care providers and policy makers to organize care for patients in the most efficient way.-
Descrição: dc.descriptionEvidence-Based Health Program Escola Paulista de Medicina Universidade Federal de São Paulo, SP-
Descrição: dc.descriptionPharmaceutical Sciences Program School of Pharmaceutical Sciences Universidade Estadual de São Paulo, SP-
Descrição: dc.descriptionDepartment of Drugs and Medicines School of Pharmaceutical Sciences Universidade Estadual de São Paulo, SP-
Descrição: dc.descriptionDepartment of Sustainability and Social Responsibility Hospital Alemão Oswaldo Cruz, SP-
Descrição: dc.descriptionEscola Paulista de Medicina Universidade Federal de São Paulo, SP-
Descrição: dc.descriptionFaculdade de Medicina Universidade de Santo Amaro, SP-
Descrição: dc.descriptionDepartment of Biological and Health Sciences Universidade Federal do Amapá, AP-
Descrição: dc.descriptionDepartment of Medical Practices Beneficência Portuguesa de São Paulo, SP-
Descrição: dc.descriptionDiscipline of Infectiology Escola Paulista de Medicina Universidade Federal de São Paulo, SP-
Descrição: dc.descriptionDiscipline of Emergency and Evidence-Based Medicine Escola Paulista de Medicina Universidade Federal de São Paulo, SP-
Descrição: dc.descriptionPharmaceutical Sciences Program School of Pharmaceutical Sciences Universidade Estadual de São Paulo, SP-
Descrição: dc.descriptionDepartment of Drugs and Medicines School of Pharmaceutical Sciences Universidade Estadual de São Paulo, SP-
Idioma: dc.languageen-
Relação: dc.relationPLoS ONE-
???dc.source???: dc.sourceScopus-
Título: dc.titleHospitalization costs of coronaviruses diseases in upper-middle-income countries: A systematic review-
Tipo de arquivo: dc.typevídeo-
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