Evaluation of Two Beta-Tricalcium Phosphates with Different Particle Dimensions in Human Maxillary Sinus Floor Elevation: A Prospective, Randomized Clinical Trial

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversity of Grande Rio—UNIGRANRIO-
Autor(es): dc.contributorFluminense Federal University-
Autor(es): dc.creatorMendes, Bruno Coelho-
Autor(es): dc.creatorPereira, Rodrigo Dos Santos-
Autor(es): dc.creatorMourão, Carlos Fernando de Almeida Barros-
Autor(es): dc.creatorMontemezzi, Pietro-
Autor(es): dc.creatorSantos, Anderson Maikon de Souza-
Autor(es): dc.creatorMoreno, Jéssica Monique Lopes-
Autor(es): dc.creatorOkamoto, Roberta-
Autor(es): dc.creatorHochuli-Vieira, Eduardo-
Data de aceite: dc.date.accessioned2025-08-21T16:59:41Z-
Data de disponibilização: dc.date.available2025-08-21T16:59:41Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-03-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/ma15051824-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/230513-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/230513-
Descrição: dc.descriptionThis study aimed to compare two beta-tricalcium phosphates with different particle sizes in human maxillary sinuses lifting. The immunolabeling of cells for RUNX2 and VEGF were performed to evaluate the osteoblast precursor cells and the vascular formation after 6 months of bone repair. Ten maxillary sinuses were grafted with autogenous bone graft (Group 1), 10 were grafted with ChronOs® (Group 2), and 10 were grafted with BETA-TCP® (Group 3). After 6 months of bone healing, biopsies were obtained to assess the new bone formed by histomorphometric and immunohistochemical evaluation for RUNX2 and VEGF. The mean bone formation for Group 1 was 51.4 ± 17.4%. Group 2 presented 45.5 ± 9.9%, and Group 3 conferred 35.4 ± 8.0% of new bone formation. The RUNX2 offered low for Groups 1 and 2 with high cellular activity for osteoblast in Group 3. The VEGF immunolabeling was moderate for Groups 1 and 2 and intense for Group 3. In conclusion, it was possible to show that the bone substitutes evaluated in the present study presented suitable outcomes for bone regeneration, being an alternative for the autogenous bone graft in maxillary sinus bone height reconstruction.-
Descrição: dc.descriptionDepartment of Oral & Maxillofacial Surgery Aracatuba School of Dentistry Sao Paulo State University-
Descrição: dc.descriptionDepartment of Oral & Maxillofacial Surgery University of Grande Rio—UNIGRANRIO-
Descrição: dc.descriptionClinical Research Unit of the Antonio Pedro Hospital Fluminense Federal University-
Descrição: dc.descriptionDepartment of Dental Prosthesis Aracatuba School of Dentistry Sao Paulo State University-
Descrição: dc.descriptionDepartment of Human Anatomy Aracatuba School of Dentistry Sao Paulo State University-
Descrição: dc.descriptionDepartment of Oral & Maxillofacial Surgery Aracatuba School of Dentistry Sao Paulo State University-
Descrição: dc.descriptionDepartment of Dental Prosthesis Aracatuba School of Dentistry Sao Paulo State University-
Descrição: dc.descriptionDepartment of Human Anatomy Aracatuba School of Dentistry Sao Paulo State University-
Idioma: dc.languageen-
Relação: dc.relationMaterials-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBiomaterials-
Palavras-chave: dc.subjectBone substitutes-
Palavras-chave: dc.subjectSinus floor augmentation-
Título: dc.titleEvaluation of Two Beta-Tricalcium Phosphates with Different Particle Dimensions in Human Maxillary Sinus Floor Elevation: A Prospective, Randomized Clinical Trial-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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