Clinicopathological and prognostic profile of non-smoking and non-drinking head and neck cancer patients: a population-based comparative study

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorBonetti Valente, Vitor-
Autor(es): dc.creatorMantovan Mazzon, Bruna-
Autor(es): dc.creatorUrbano Collado, Francisco-
Autor(es): dc.creatorConrado Neto, Sebastião-
Autor(es): dc.creatorLúcia Marçal Mazza Sundefeld, Maria-
Autor(es): dc.creatorRicardo Biasoli, Éder-
Autor(es): dc.creatorIssamu Miyahara, Glauco-
Autor(es): dc.creatorGalera Bernabé, Daniel-
Data de aceite: dc.date.accessioned2025-08-21T18:24:18Z-
Data de disponibilização: dc.date.available2025-08-21T18:24:18Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.oraloncology.2022.105799-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/230507-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/230507-
Descrição: dc.descriptionTobacco and alcohol consumption are the main risk factors for head and neck cancer (HNC). However, some individuals do not have a history of addiction and even so they develop the disease. This study evaluated clinicopathological and prognostic features of non-smoking and non-drinking (NSND) HNC patients. A sample of smoking and/or drinking (SD) HNC patients was used to explore the differences with NSND patients. Data were obtained from 667 patients with squamous cell carcinoma in oral cavity, oropharynx or larynx. The group of NSND individuals represented 12.6% of the HNC patients and had higher prevalence of women and elderly compared to SD group. Among NSND patients, most of them displayed tumors in oral cavity, advanced clinical staging and absence of second primary tumor. NSND HNC patients had higher tumor recurrence and increased overall and specific survival rates at 5-years follow-up. The NSND group showed higher prevalence of tumors in lips and alveolar ridge, lower rate of tumors in floor of mouth and no tumor in soft palate. NSND patients show a distinct profile from that found in SD patients. Clinicopathological features from NSND patients should be considered for HNC management.-
Descrição: dc.descriptionOral Oncology Center São Paulo State University (Unesp) School of Dentistry, 1193 José Bonifácio St, São Paulo-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery São Paulo State University (Unesp) School of Dentistry, 1193 José Bonifácio St, São Paulo-
Descrição: dc.descriptionOral Oncology Center São Paulo State University (Unesp) School of Dentistry, 1193 José Bonifácio St, São Paulo-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery São Paulo State University (Unesp) School of Dentistry, 1193 José Bonifácio St, São Paulo-
Idioma: dc.languageen-
Relação: dc.relationOral Oncology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAlcohol-
Palavras-chave: dc.subjectClinicopathological features-
Palavras-chave: dc.subjectHead and neck cancer-
Palavras-chave: dc.subjectLarynx cancer-
Palavras-chave: dc.subjectOral cancer-
Palavras-chave: dc.subjectOropharynx cancer-
Palavras-chave: dc.subjectPrognosis-
Palavras-chave: dc.subjectRisk factors-
Palavras-chave: dc.subjectSmoking-
Palavras-chave: dc.subjectTobacco-
Título: dc.titleClinicopathological and prognostic profile of non-smoking and non-drinking head and neck cancer patients: a population-based comparative study-
Tipo de arquivo: dc.typetexto-
Aparece nas coleções:Repositório Institucional - Unesp

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