Cryosurgery with liquid nitrogen versus trichloroacetic acid in the treatment of human papillomavirus (HPV) penile wart: a randomized controlled trial

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorMorita, Mariana M.-
Autor(es): dc.creatorMarcondes, Thomas S. P.-
Autor(es): dc.creatorHaddad, Vidal-
Autor(es): dc.creatorMiot, Hélio Amante-
Data de aceite: dc.date.accessioned2025-08-21T17:41:36Z-
Data de disponibilização: dc.date.available2025-08-21T17:41:36Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2020-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.5935/SCD1984-8773.2021130041-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/230439-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/230439-
Descrição: dc.descriptionBackground: Anogenital warts are the most prevalent sexually transmitted infection (0.5%) among dermatological consultations. Cryotherapy with liquid nitrogen (LN) and therapy with trichloroacetic acid (TCA) are remarkable among the treatment strategies. Objective: To evaluate the effectiveness of LN versus TCA in to treat penile warts in patients from a Brazilian public institution. Methods: Open, parallel, randomized clinical trial. Following randomization, the warts were counted and submitted to cryotherapy (10s) or case therapy (TCA 80%) in each visit. The primary dependent variable was the lesion count before and after four weeks of treatment. We assessed the following variables: complete clearance, age, immunosuppression, smoking, topography, and education. Results: 142 treatments were evaluated in 52 participants. There was a predominance of young adults, and the main topography affected was the penis shaft. The mean reduction rate per session was 48% for LN and 26% for TCA (p=0.11). 42 (81%) participants achieved complete clearance, with 39 (75%; 95% CI: 64-85%) reaching clearance in up to three sessions. Age was associated with a worse therapeutic response rate (ß =-0.09; p<0.01). Conclusions: LN and TCA proved to be effective to treat penile warts, without difference between treatments. Age was associated with a worse therapeutic response.-
Descrição: dc.descriptionUniversidade Estadual de São Paulo Department of Dermatology, SP-
Descrição: dc.descriptionUniversidade Estadual de São Paulo Department of Dermatology, SP-
Idioma: dc.languageen-
Relação: dc.relationSurgical and Cosmetic Dermatology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCryosurgery-
Palavras-chave: dc.subjectPapillomavirus infections-
Palavras-chave: dc.subjectSexually transmitted diseases-
Palavras-chave: dc.subjectTrichloroacetic acid-
Palavras-chave: dc.subjectWarts-
Título: dc.titleCryosurgery with liquid nitrogen versus trichloroacetic acid in the treatment of human papillomavirus (HPV) penile wart: a randomized controlled trial-
Título: dc.titleCriocirurgia com nitrogênio líquido versus ácido tricloroacético no tratamento de verruga peniana por papilomavírus humano (HPV): um ensaio clínico randomizado-
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Aparece nas coleções:Repositório Institucional - Unesp

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