Genomic study of the resilience of buffalo cows to a negative energy balance

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorCiência e Tecnologia Goiano - IFGoiano-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade Tecnologica Federal do Paraná – UTFPR-
Autor(es): dc.contributorUniversity of New England-
Autor(es): dc.creatorde Araujo Neto, Francisco Ribeiro-
Autor(es): dc.creatordos Santos, Jessica Cristina Gonçalves-
Autor(es): dc.creatorda Silva Arce, Cherlynn Daniela-
Autor(es): dc.creatorBorquis, Rusbel Raul Ascpilcueta-
Autor(es): dc.creatordos Santos, Daniel Jordan Abreu-
Autor(es): dc.creatorGuimarães, Katia Cylene-
Autor(es): dc.creatordo Nascimento, André Vieira-
Autor(es): dc.creatorde Oliveira, Henrique Nunes-
Autor(es): dc.creatorTonhati, Humberto-
Data de aceite: dc.date.accessioned2025-08-21T16:52:38Z-
Data de disponibilização: dc.date.available2025-08-21T16:52:38Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2021-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s13353-021-00680-x-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/230273-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/230273-
Descrição: dc.descriptionThe research article was carried out with the objective of studying the genetic variation on the resilience of buffaloes to negative energy balance—NEB (measured by changes in body weight in early lactation)—as well as investigating genomic regions of interest for this trait. A model of reaction norms was used, considering milk production as the trait to be analyzed and solutions of the contemporary groups to weight changes as environmental gradient. In this methodology, the genetic value of the slope represents the measure of resilience of the animals. After the estimation step, a genome-wide association analysis was performed for the slope of the reaction norms model, to obtain a list of windows and associated genes. The heritability estimates for milk production over the resilience gradient ranged from 0.13 to 0.28, with lower values in the intermediate environmental groups. Regarding the productive resilience of dairy buffalo cows to NEB, the genomic windows with the highest contribution to the genetic variance were detected on chromosomes BBU 1, 2, 3, 4, 9, 12, 19, and 21. A functional analysis of the genes described in the selected windows indicated association with metabolic routes related to growth and immunity of the animals, with an emphasis on the STAT6 gene. The results presented indicate that there is for this trait genetic variation to be used as selection criteria, in addition to genomic regions that can increase the precision of the selection.-
Descrição: dc.descriptionInstituto Federal de Educação Ciência e Tecnologia Goiano - IFGoiano, Goias-
Descrição: dc.descriptionDepartament of Animal Science Universidade Estadual Paulista “Julio de Mesquita” – UNESP, Jaboticabal-
Descrição: dc.descriptionUniversidade Tecnologica Federal do Paraná – UTFPR, Paraná-
Descrição: dc.descriptionAnimal Genetics and Breeding Unit University of New England-
Descrição: dc.descriptionDepartament of Animal Science Universidade Estadual Paulista “Julio de Mesquita” – UNESP, Jaboticabal-
Idioma: dc.languageen-
Relação: dc.relationJournal of Applied Genetics-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBubalus bubalis-
Palavras-chave: dc.subjectGWAS-
Palavras-chave: dc.subjectProduction efficiency-
Palavras-chave: dc.subjectssGBLUP-
Título: dc.titleGenomic study of the resilience of buffalo cows to a negative energy balance-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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