Biocompatibility and immunolabeling of fibronectin and tenascin of resinous root canal sealersw

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorState University of Northern Paraná-
Autor(es): dc.contributorUniversidade Federal de Minas Gerais (UFMG)-
Autor(es): dc.creatorCosta, Vanessa Abreu Sanches Marques-
Autor(es): dc.creatorBueno, Carlos Roberto Emerenciano-
Autor(es): dc.creatorValentim, Diego-
Autor(es): dc.creatorBenetti, Francine-
Autor(es): dc.creatorCury, Marina Tolomei Sandoval-
Autor(es): dc.creatorVasques, Ana Maria Veiga-
Autor(es): dc.creatorErvolino, Edilson-
Autor(es): dc.creatorDezan-Junior, Eloi-
Data de aceite: dc.date.accessioned2025-08-21T16:28:21Z-
Data de disponibilização: dc.date.available2025-08-21T16:28:21Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2021-07-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.4103/jcd.jcd_628_20-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/230264-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/230264-
Descrição: dc.descriptionAims: The aim of this study was to evaluate the biocompatibility of resinous root canal sealers: Sealer 26, AH plus, and SK Seal Root Canal Sealer in the subcutaneous tissue of rats. Subjects and Methods: Twenty-four Wistar rats received polyethylene tubes containing the sealers and empty tubes as control (n = 6). After 7, 15, 30, and 60 days, animals were killed and polyethylene tubes were removed with the surrounding tissues. The specimens were embedded in paraffin, processed for hematoxylin-eosin and immunohistochemistry assessed for fibronectin (FN) and tenascin (TN). Statistical Analysis Used: Data were tabulated and analyzed via Kruskal-Wallis and Dunn's test (P < 0.05). Results: All groups induced a moderate inflammatory reaction after 7 and 15 days (P > 0.05); after 30 days, a mild inflammatory infiltrate was observed in control groups, and moderate in sealers groups (P > 0.05); all groups showed mild inflammatory infiltrate at 60 days (P > 0.05). Overall, the fibrous capsule was considered thick only on the 7 th day and became thin over time. All groups had expression for FN and TN in all analyzed periods, with high immunolabeling in sealers groups when comparing with the control group (P < 0.05). Conclusion: All sealers demonstrated biocompatibility and induced FN and TN expression.-
Descrição: dc.descriptionDepartment of Endodontics School of Dentistry São Paulo State University (UNESP), Araçatuba, SP-
Descrição: dc.descriptionDepartment of Odontology State University of Northern Paraná, Jacarezinho, PR-
Descrição: dc.descriptionDepartment of Restorative Dentistry School of Dentistry UFMG-Universidade Federal de Minas Gerais, Belo Horizonte, MG-
Descrição: dc.descriptionBasic Science School of Dentistry São Paulo State University (UNESP), Araçatuba, SP-
Descrição: dc.descriptionDepartment of Endodontics School of Dentistry São Paulo State University (UNESP), Araçatuba, SP-
Descrição: dc.descriptionBasic Science School of Dentistry São Paulo State University (UNESP), Araçatuba, SP-
Formato: dc.format323-329-
Idioma: dc.languageen-
Relação: dc.relationJournal of Conservative Dentistry-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBiocompatibility-
Palavras-chave: dc.subjectMaterials testing-
Palavras-chave: dc.subjectTenascin-
Título: dc.titleBiocompatibility and immunolabeling of fibronectin and tenascin of resinous root canal sealersw-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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