Patients with Classical Hodgkin Lymphoma with Less Than 10.5 CD20-Positive Reed–Sternberg Cells in 10 High-Power Fields Have Better Prognosis

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorLuxemburgo Hospital-
Autor(es): dc.contributorSão Luiz/D’Or Hospital-
Autor(es): dc.creatorLacet, Dominique Fonseca Rodrigues-
Autor(es): dc.creatorOliveira, Cristiano Claudino-
Data de aceite: dc.date.accessioned2025-08-21T16:25:16Z-
Data de disponibilização: dc.date.available2025-08-21T16:25:16Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2021-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s12288-021-01517-7-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/230206-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/230206-
Descrição: dc.descriptionThe CD20 immunoexpression in classical Hodgkin lymphoma (CHL) is variable and it may represent an intersection between the pathophysiology of CHL and the clinical prognosis of patients. Retrospective study with 174 patients with pathological diagnosis of CHL. Clinical data were reviewed from medical records. Immunophenotypic study with CD20 were performed in two ways: hotspot count and in 10 high-power fields (HPF). The data were tabulated and the p value less than 0.05 was considered significant. The CD20-positive phenotype was found in 45 (25.9%) of the total of 174 patients with available material. Patients with CD20 positivity on neoplastic cells tend to heal earlier, particularly those with less than 10.5 cells/10 HPF (p = 0.037). Patients with CHL with less than 10.5 CD20-positive Reed-Sternberg cells in 10 HPF have better prognosis.-
Descrição: dc.descriptionDepartment of Pathology Botucatu School of Medicine São Paulo State University (FMB UNESP)-
Descrição: dc.descriptionDepartment of Pathology Luxemburgo Hospital, Rua Gentios, 1350, Luxemburgo, Minas Gerais-
Descrição: dc.descriptionDepartment of Pathology São Luiz/D’Or Hospital-
Descrição: dc.descriptionDepartment of Pathology Botucatu School of Medicine São Paulo State University (FMB UNESP)-
Idioma: dc.languageen-
Relação: dc.relationIndian Journal of Hematology and Blood Transfusion-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCD20 antigen-
Palavras-chave: dc.subjectHodgkin disease-
Palavras-chave: dc.subjectImmunohistochemistry-
Palavras-chave: dc.subjectPatient outcome assessment-
Palavras-chave: dc.subjectPrognosis-
Título: dc.titlePatients with Classical Hodgkin Lymphoma with Less Than 10.5 CD20-Positive Reed–Sternberg Cells in 10 High-Power Fields Have Better Prognosis-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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