Oxidative Stress Profile of Mothers and Their Offspring after Maternal Consumption of High-Fat Diet in Rodents: A Systematic Review and Meta-Analysis

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade Federal de Mato Grosso do Sul (UFMS)-
Autor(es): dc.contributorInstitut Universitaire de Gériatrie de Montréal-
Autor(es): dc.creatorMoraes-Souza, R. Q.-
Autor(es): dc.creatorVesentini, Giovana-
Autor(es): dc.creatorPaula, Verônyca Gonçalves-
Autor(es): dc.creatorSinzato, Yuri Karen-
Autor(es): dc.creatorSoares, T. S.-
Autor(es): dc.creatorGelaleti, Rafael Bottaro-
Autor(es): dc.creatorVolpato, Gustavo Tadeu-
Autor(es): dc.creatorDamasceno, Débora Cristina-
Data de aceite: dc.date.accessioned2025-08-21T20:31:52Z-
Data de disponibilização: dc.date.available2025-08-21T20:31:52Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2020-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1155/2021/9073859-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/230029-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/230029-
Descrição: dc.descriptionMaternal exposure to the high-fat diet (HFD) during gestation or lactation can be harmful to both a mother and offspring. The aim of this systematic review was to identify and evaluate the studies with animal models (rodents) that were exposed to the high-fat diet during pregnancy and/or lactation period to investigate oxidative stress and lipid and liver enzyme profile of mothers and their offspring. The electronic search was performed in the PUBMED (Public/Publisher MEDLINE), EMBASE (Ovid), and Web of Science databases. Data from 77 studies were included for qualitative analysis, and of these, 13 studies were included for meta-analysis by using a random effects model. The pooled analysis revealed higher malondialdehyde levels in offspring of high-fat diet groups. Furthermore, the pooled analysis showed increased reactive oxygen species and lower superoxide dismutase and catalase in offspring of mothers exposed to high-fat diet during pregnancy and/or lactation. Despite significant heterogeneity, the systematic review shows oxidative stress in offspring induced by maternal HFD.-
Descrição: dc.descriptionLaboratory of Experimental Research on Gynecology and Obstetrics Gynecology Postgraduate Course on Tocogynecology Botucatu Medical School São Paulo State University (Unesp), São Paulo State-
Descrição: dc.descriptionLaboratory of System Physiology and Reproductive Toxicology Institute of Biological and Health Sciences Federal University of Mato Grosso (UFMT), Mato Grosso State-
Descrição: dc.descriptionSchool of Rehabilitation Faculty of Medicine Université de Montréal Research Center Institut Universitaire de Gériatrie de Montréal-
Descrição: dc.descriptionLaboratory of Experimental Research on Gynecology and Obstetrics Gynecology Postgraduate Course on Tocogynecology Botucatu Medical School São Paulo State University (Unesp), São Paulo State-
Idioma: dc.languageen-
Relação: dc.relationOxidative Medicine and Cellular Longevity-
???dc.source???: dc.sourceScopus-
Título: dc.titleOxidative Stress Profile of Mothers and Their Offspring after Maternal Consumption of High-Fat Diet in Rodents: A Systematic Review and Meta-Analysis-
Tipo de arquivo: dc.typelivro digital-
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