Effect of low-level laser therapy on the membrane induced by the masquelet technique at an orthotopic site in rabbits

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorCoris, Jeniffer Gabriela Figueroa-
Autor(es): dc.creatorRahal, Sheila Canevese-
Autor(es): dc.creatorFonseca-Alves, Carlos Eduardo-
Autor(es): dc.creatorMamprim, Maria Jaqueline-
Autor(es): dc.creatorInamassu, Letícia Rocha-
Autor(es): dc.creatorde Abreu Sampaio, Alexandre Botelho-
Autor(es): dc.creatorKano, Washington Takashi-
Autor(es): dc.creatorMesquita, Luciane Dos Reis-
Autor(es): dc.creatorJunior, José Ivaldo de Siqueira Silva-
Data de aceite: dc.date.accessioned2025-08-21T22:00:54Z-
Data de disponibilização: dc.date.available2025-08-21T22:00:54Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2020-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1590/ACB361003-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/229952-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/229952-
Descrição: dc.descriptionPurpose: To evaluate the low-level laser therapy (LLLT) on the membrane induced by the Masquelet technique in rabbits. Methods: Twelve Norfolk rabbits at approximately 3 months of age were used. A 1-cm segmental defect was induced in both radii, which were filled with polymethylmethacrylate cylinder. LLLT was used postoperatively in the bone defect of one of the forelimbs every 48 hours for 15 days. Six rabbits were euthanatized on third and sixth postoperative weeks. Results: In both forelimbs, radiographs showed new bone growth from radius cut ends on the third postoperative week and more advanced stage on the sixth postoperative week. Ultrasound showed induced membrane one week after the surgery. Histologically, there were no significant differences in the semi-quantitative score of inflammation intensity, total number of blood vessels, bone metaplasia, and collagen. The average thicknesses were 2,050.17 and 1,451.96 μm for control membranes and 2,724.26 and 2,081.03 μm for irradiated membranes, respectively, on third and sixth postoperative weeks. Vascular endothelial growth factor A (VEGF-A) and platelet derived growth factor (PDGF) expression were present in the induced membranes of control and irradiated forelimbs, but there was no significant difference. Conclusion: Based on assessment methods, it was not possible to demonstrate the effect of LLLT on the induced membrane.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionAnimal Biotechnology-Department of Veterinary Surgery and Animal Reproduction School of Veterinary Medicine and Animal Science Universidade Estadual Paulista (UNESP)-
Descrição: dc.descriptionDepartment of Veterinary Surgery and Animal Reproduction School of Veterinary Medicine and Animal Science Universidade Estadual Paulista (UNESP)-
Descrição: dc.descriptionAnimal Biotechnology-Department of Veterinary Surgery and Animal Reproduction School of Veterinary Medicine and Animal Science Universidade Estadual Paulista (UNESP)-
Descrição: dc.descriptionDepartment of Veterinary Surgery and Animal Reproduction School of Veterinary Medicine and Animal Science Universidade Estadual Paulista (UNESP)-
Descrição: dc.descriptionCAPES: 001-
Descrição: dc.descriptionFAPESP: 2019/01750-0-
Idioma: dc.languageen-
Relação: dc.relationActa Cirurgica Brasileira-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectInfrared rays-
Palavras-chave: dc.subjectLow-level light therapy-
Palavras-chave: dc.subjectOrthopedics-
Palavras-chave: dc.subjectRabbits-
Título: dc.titleEffect of low-level laser therapy on the membrane induced by the masquelet technique at an orthotopic site in rabbits-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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