Effectiveness of 1-Visit and 2-Visit Endodontic Retreatment of Teeth with Persistent/Secondary Endodontic Infection: A Randomized Clinical Trial with 18 Months of Follow-up

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorToia, Cassia Cestari-
Autor(es): dc.creatorKhoury, Rayana Duarte-
Autor(es): dc.creatorCorazza, Bruna Jordão Motta-
Autor(es): dc.creatorOrozco, Esteban Isai Flores-
Autor(es): dc.creatorValera, Marcia Carneiro-
Data de aceite: dc.date.accessioned2025-08-21T19:26:02Z-
Data de disponibilização: dc.date.available2025-08-21T19:26:02Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2021-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.joen.2021.09.004-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/229792-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/229792-
Descrição: dc.descriptionIntroduction: This randomized clinical trial aimed to compare the effectiveness of endodontic retreatment of teeth with posttreatment apical periodontitis (PTAP) performed in 1 visit versus 2 visits on the reduction of cultivable bacteria (colony-forming units [CFUs]), lipopolysaccharides (LPSs), lipoteichoic acid (LTA), and the periapical lesion volume (mm3) after 18 months of follow-up. Methods: Forty patients diagnosed with PTAP were selected and randomly divided into the following 2 groups: 1-visit retreatment and 2-visit retreatment with the placement of calcium hydroxide medication for 14 days. Cone-beam computed tomographic scans were performed at 2 stages: preoperatively and after 18 months of follow-up. Samples were collected before and after root canal procedures. A chromogenic limulus amebocyte lysate assay test was used to quantify endotoxins (EU/mL). LTA levels were measured using the enzyme-linked immunosorbent assay (pg/mL). Culture techniques were used to determine cultivable bacteria by counting the CFU (CFU/mL). The volume of the periapical lesions at the onset of the trial and at the 18-month posttreatment follow-up was obtained by the ITK-SNAP program (Cognitica, Philadelphia, PA). Results: All samples showed baseline values greater than those collected after the retreatment protocol for all investigated parameters. A higher bacterial load and lower LTA level were found in the 2-visit group after the retreatment protocol (P < .05), with no statistical differences between the groups regarding endotoxin levels and periapical lesion volume (mm³) at the 18-month follow-up analyzed by cone-beam computed tomographic imaging (P > .05). Conclusions: Endodontic retreatment in 1 or 2 visits exhibited equally favorable periapical healing at 18 months, with no statistically significant differences between groups.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionDepartment of Operative Dentistry Endodontics Division Institute of Science and Technology São Paulo State University São José dos Campos-
Descrição: dc.descriptionDepartment of Operative Dentistry Endodontics Division Institute of Science and Technology São Paulo State University São José dos Campos-
Descrição: dc.descriptionFAPESP: 2014/25789-9-
Descrição: dc.descriptionFAPESP: 2017/22676-7-
Descrição: dc.descriptionFAPESP: 2018/01703-9-
Formato: dc.format4-14-
Idioma: dc.languageen-
Relação: dc.relationJournal of Endodontics-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCone-beam computed tomography-
Palavras-chave: dc.subjectlipopolysaccharides-
Palavras-chave: dc.subjectlipoteichoic acid-
Palavras-chave: dc.subjectperiapical periodontitis-
Palavras-chave: dc.subjectroot canal therapy-
Título: dc.titleEffectiveness of 1-Visit and 2-Visit Endodontic Retreatment of Teeth with Persistent/Secondary Endodontic Infection: A Randomized Clinical Trial with 18 Months of Follow-up-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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