Calcium glycerophosphate and fluoride affect the pH and inorganic composition of dual-species biofilms of Streptococcus mutans and Candida albicans

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversity of Western São Paulo (UNOESTE)-
Autor(es): dc.creatorCavazana, Thamires Priscila-
Autor(es): dc.creatorHosida, Thayse Yumi-
Autor(es): dc.creatorSampaio, Caio-
Autor(es): dc.creatorde Morais, Leonardo Antônio-
Autor(es): dc.creatorMonteiro, Douglas Roberto-
Autor(es): dc.creatorPessan, Juliano Pelim-
Autor(es): dc.creatorDelbem, Alberto Carlos Botazzo-
Data de aceite: dc.date.accessioned2025-08-21T23:02:41Z-
Data de disponibilização: dc.date.available2025-08-21T23:02:41Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2021-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.jdent.2021.103844-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/229703-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/229703-
Descrição: dc.descriptionObjectives: This study evaluated the influence of calcium glycerophosphate (CaGP), combined with or without fluoride (F), on the pH and concentrations of F, Ca, and P of dual-species biofilms of Streptococcus mutans and Candida albicans, with or without exposure to sucrose. Methods: The biofilms (n = 9) received three treatments (72, 78, and 96 h after the start of their formation) at three CaGP concentrations (0.125, 0.25, or 0.5%), with or without F at 500 ppm (as NaF). Solutions containing 500 and 1100 ppm F and artificial saliva were also tested as controls. Biofilm pH was measured, and the concentrations of F, Ca, P, and CaGP were determined (solid and fluid phases). In a parallel experiment, after the third treatment, the treated biofilms were exposed to a sucrose solution, and the pH of the medium, F, Ca, P, and CaGP was determined. Data were subjected to two-way ANOVA, followed by Fisher's LSD test (p < 0.05). Results: Treatment with CaGP and 500 ppm F led to the highest pH values and F and Ca concentrations in the biofilm biomass, both with and without sucrose exposure. CaGP without F led to higher Ca and P concentrations in the biofilm fluid. Conclusions: CaGP increased F, Ca, and P concentrations in the biofilm, and its presence promoted an increase in the pH of the medium, even after exposure to sucrose. Clinical significance: The present results elucidate the mechanism by which CaGP and F act on biofilms, further interfering with dental caries dynamics.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionSão Paulo State University (Unesp) School of Dentistry Araçatuba Department of Preventive and Restorative Dentistry-
Descrição: dc.descriptionGraduate Program in Dentistry (GPD - Master's Degree) University of Western São Paulo (UNOESTE)-
Descrição: dc.descriptionSão Paulo State University (Unesp) School of Dentistry Araçatuba Department of Preventive and Restorative Dentistry-
Descrição: dc.descriptionCAPES: 88881.068437 / 2014-01-
Idioma: dc.languageen-
Relação: dc.relationJournal of Dentistry-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBiofilms-
Palavras-chave: dc.subjectCalcium glycerophosphate-
Palavras-chave: dc.subjectCandida albicans-
Palavras-chave: dc.subjectFluoride-
Palavras-chave: dc.subjectPhosphate-
Palavras-chave: dc.subjectStreptococcus mutans-
Título: dc.titleCalcium glycerophosphate and fluoride affect the pH and inorganic composition of dual-species biofilms of Streptococcus mutans and Candida albicans-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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