Mass spectrometry-based metabolomics in microbiome investigations

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Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorSan Diego-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorBauermeister, Anelize-
Autor(es): dc.creatorMannochio-Russo, Helena-
Autor(es): dc.creatorCosta-Lotufo, Letícia V.-
Autor(es): dc.creatorJarmusch, Alan K.-
Autor(es): dc.creatorDorrestein, Pieter C.-
Data de aceite: dc.date.accessioned2025-08-21T17:17:36Z-
Data de disponibilização: dc.date.available2025-08-21T17:17:36Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-03-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1038/s41579-021-00621-9-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/229554-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/229554-
Descrição: dc.descriptionMicrobiotas are a malleable part of ecosystems, including the human ecosystem. Microorganisms affect not only the chemistry of their specific niche, such as the human gut, but also the chemistry of distant environments, such as other parts of the body. Mass spectrometry-based metabolomics is one of the key technologies to detect and identify the small molecules produced by the human microbiota, and to understand the functional role of these microbial metabolites. This Review provides a foundational introduction to common forms of untargeted mass spectrometry and the types of data that can be obtained in the context of microbiome analysis. Data analysis remains an obstacle; therefore, the emphasis is placed on data analysis approaches and integrative analysis, including the integration of microbiome sequencing data.-
Descrição: dc.descriptionInstitute of Biomedical Science Universidade de São Paulo-
Descrição: dc.descriptionCollaborative Mass Spectrometry Innovation Center Skaggs School of Pharmacy and Pharmaceutical Sciences University of California San Diego-
Descrição: dc.descriptionDepartment of Biochemistry and Organic Chemistry Institute of Chemistry São Paulo State University-
Descrição: dc.descriptionDepartment of Pediatrics University of California San Diego-
Descrição: dc.descriptionCenter for Microbiome Innovation University of California San Diego-
Descrição: dc.descriptionDepartment of Biochemistry and Organic Chemistry Institute of Chemistry São Paulo State University-
Formato: dc.format143-160-
Idioma: dc.languageen-
Relação: dc.relationNature Reviews Microbiology-
???dc.source???: dc.sourceScopus-
Título: dc.titleMass spectrometry-based metabolomics in microbiome investigations-
Tipo de arquivo: dc.typevídeo-
Aparece nas coleções:Repositório Institucional - Unesp

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