Bioadhesive curcumin-mediated photodynamic inactivation and its potential to cause undesirable effects on dental and restorative surfaces

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorthe Moment of the Submission (Unaffiliated Researcher)-
Autor(es): dc.contributorUniversidade Estadual de Campinas (UNICAMP)-
Autor(es): dc.creatorReina, Bárbara Donadon-
Autor(es): dc.creatorNeto, Carolina Santezi-
Autor(es): dc.creatorGarcia, Patrícia Petromilli Nordi Sasso-
Autor(es): dc.creatorChorilli, Marlus-
Autor(es): dc.creatorCalixto, Giovana Maria Fioramonti-
Autor(es): dc.creatorDovigo, Lívia Nordi-
Data de aceite: dc.date.accessioned2025-08-21T16:44:23Z-
Data de disponibilização: dc.date.available2025-08-21T16:44:23Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2021-09-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/pharmaceutics13091458-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/229526-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/229526-
Descrição: dc.descriptionCurcumin-mediated Photodynamic Inactivation (PDI) has shown great potential to disinfect specific sites on tooth enamel but may involve contact with restorative materials. Thus, before use in dentistry, it is necessary to investigate whether the PDI protocol causes undesirable changes in the surfaces of aesthetic restorative materials and dental enamel. This study investigated the effect of PDI mediated by curcumin (CUR) in a liquid crystal precursor system on color stability (∆E), surface roughness (Ra), and microhardness (kgf) of three different composite resins and bovine dental enamel specimens. The microhardness and roughness readings were performed 60 days after the treatments while the color readings were performed immediately, 24, 48, and 72 h, 7, 14, 21, 30, and 60 days after the treatments. Results showed that CUR mediated-PDI does not seem to have the potential to promote any esthetic or mechanical changes to the surface of tooth enamel and can be applied safely in clinical practice. However, the results on color, roughness, and hardness obtained for composite resins show that some negative effects can be produced, depending on the type of restorative material; more experiments must be performed with different formulations and, perhaps, with lower concentrations of CUR.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionDepartment of Social Dentistry School of Dentistry São Paulo State University (UNESP), Rua Humaitá 1680-
Descrição: dc.descriptionIndependent Researcher the Moment of the Submission (Unaffiliated Researcher)-
Descrição: dc.descriptionDepartment of Drugs and Medicines School of Pharmacy São Paulo State University (UNESP), Rodovia Araraquara-Jaú, Km. 1-
Descrição: dc.descriptionDepartment of Biosciences Piracicaba Dental School University of Campinas (UNICAMP), Avenida Limeira-
Descrição: dc.descriptionDepartment of Social Dentistry School of Dentistry São Paulo State University (UNESP), Rua Humaitá 1680-
Descrição: dc.descriptionDepartment of Drugs and Medicines School of Pharmacy São Paulo State University (UNESP), Rodovia Araraquara-Jaú, Km. 1-
Descrição: dc.descriptionFAPESP: 2013/15770-6-
Idioma: dc.languageen-
Relação: dc.relationPharmaceutics-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectComposite resins-
Palavras-chave: dc.subjectCurcumin-
Palavras-chave: dc.subjectLiquid crystals-
Palavras-chave: dc.subjectPhotochemotherapy-
Palavras-chave: dc.subjectPhotosensitizing agents-
Título: dc.titleBioadhesive curcumin-mediated photodynamic inactivation and its potential to cause undesirable effects on dental and restorative surfaces-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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