Pain modulated by Bothrops snake venoms: Mechanisms of nociceptive signaling and therapeutic perspectives

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorFederal University of ABC-
Autor(es): dc.creatorCavalcante, Joeliton dos Santos-
Autor(es): dc.creatorNogueira Júnior, Francisco Assis-
Autor(es): dc.creatorBezerra Jorge, Roberta Jeane-
Autor(es): dc.creatorAlmeida, Cayo-
Data de aceite: dc.date.accessioned2025-08-21T21:44:33Z-
Data de disponibilização: dc.date.available2025-08-21T21:44:33Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2021-10-15-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.toxicon.2021.08.016-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/229435-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/229435-
Descrição: dc.descriptionSnake venoms are substances mostly composed by proteins and peptides with high biological activity. Local and systemic effects culminate in clinical manifestations induced by these substances. Pain is the most uncomfortable condition, but it has not been well investigated. This review discusses Bothrops snakebite-induced nociception, highlighting molecules involved in the mediation of this process and perspectives in treatment of pain induced by Bothrops snake venoms (B. alternatus, B. asper, B. atrox, B. insularis, B. jararaca, B. pirajai, B. jararacussu, B. lanceolatus, B. leucurus, B. mattogrossensis, B. moojeni). We highlight, the understanding of the nociceptive signaling, especially in snakebite, enables more efficient treatment approaches. Finally, future perspectives for pain treatment concerning snakebite patients are discussed.-
Descrição: dc.descriptionGraduate Program in Tropical Diseases Botucatu Medical School (FMB) São Paulo State University-
Descrição: dc.descriptionDepartment of Physiology and Pharmacology and Drug Research and Development Center Federal University of Ceará-
Descrição: dc.descriptionCenter of Mathematics Computing Sciences and Cognition Federal University of ABC-
Descrição: dc.descriptionGraduate Program in Tropical Diseases Botucatu Medical School (FMB) São Paulo State University-
Formato: dc.format105-114-
Idioma: dc.languageen-
Relação: dc.relationToxicon-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBothrops-
Palavras-chave: dc.subjectInflammation-
Palavras-chave: dc.subjectNociception-
Palavras-chave: dc.subjectSnakebite-
Palavras-chave: dc.subjectTissue damage-
Título: dc.titlePain modulated by Bothrops snake venoms: Mechanisms of nociceptive signaling and therapeutic perspectives-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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