Spongiotic hyperplasia of the oral mucosa: case series and immunohistochemical analysis

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorNational Autonomous University of Mexico-
Autor(es): dc.contributorUniversidade Vale Do Rio Verde (UninCor)-
Autor(es): dc.creatorSilveira, Heitor Albergoni-
Autor(es): dc.creatorToral-Rizo, Victor Hugo-
Autor(es): dc.creatorLara-Carrillo, Edith-
Autor(es): dc.creatorDominguete, Matheus Henrique Lopes-
Autor(es): dc.creatorSilva, Evânio Vilela-
Autor(es): dc.creatorRibeiro-Silva, Alfredo-
Autor(es): dc.creatorBufalino, Andreia-
Autor(es): dc.creatorAlmeida, Luciana Yamamoto-
Autor(es): dc.creatorLeón, Jorge Esquiche-
Data de aceite: dc.date.accessioned2025-08-21T19:43:32Z-
Data de disponibilização: dc.date.available2025-08-21T19:43:32Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2020-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s10006-021-00996-2-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/229330-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/229330-
Descrição: dc.descriptionThe localized juvenile spongiotic gingival hyperplasia (LJSGH) mainly affects the maxillary vestibular attached gingiva of juvenile patients, without sex predilection. Similar lesions involving extragingival sites have not been reported to date. Here, we report 2 cases of extragingival soft tissue lesions with similar clinicopathological features to those reported in LJSGH and 12 cases of intraoral reactive soft tissue lesions microscopically showing LJSGH-like focal areas. The 2 cases were adult patients, affecting the maxillary alveolar ridge (55-year-old female) and hard palate (78-year-old male), which were diagnosed as “spongiotic hyperplasia of the oral mucosa.” The 12 intraoral reactive soft tissue lesions (6 men and 6 women; mean age, 49.5 years) were diagnosed as inflammatory fibrous hyperplasia (n = 6), peripheral ossifying fibroma (n = 3), and pyogenic granuloma (n = 3), each of them presenting LJSGH-like focal areas. By immunohistochemistry, the spongiotic hyperplasia areas showed positivity for CK19, CK14, CK34βE12, and CAM5.2 (weak/focal), while CK4 was negative. Considering the anatomical locations (extragingival) of these 2 cases, the term “spongiotic hyperplasia of the oral mucosa” is suggested. Moreover, LJSGH-like focal areas can be detected when microscopically assessing common intraoral reactive soft tissue lesions.-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery Araraquara Dental School São Paulo State University (UNESP)-
Descrição: dc.descriptionOral Pathology Department of Stomatology Public Oral Health and Forensic Dentistry Ribeirão Preto Dental School (FORP/USP) University of São Paulo-
Descrição: dc.descriptionSchool of Dentistry National Autonomous University of Mexico-
Descrição: dc.descriptionUniversidade Vale Do Rio Verde (UninCor)-
Descrição: dc.descriptionDepartment of Pathology and Forensic Medicine Ribeirão Preto Medical School (FMRP/USP) University of São Paulo-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery Univ Estadual Paulista (UNESP), Rua Humaitá, 1680-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery Araraquara Dental School São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery Univ Estadual Paulista (UNESP), Rua Humaitá, 1680-
Idioma: dc.languageen-
Relação: dc.relationOral and Maxillofacial Surgery-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectImmunohistochemistry-
Palavras-chave: dc.subjectLocalized juvenile spongiotic gingival hyperplasia-
Palavras-chave: dc.subjectOral mucosa-
Palavras-chave: dc.subjectReactive soft tissue lesions-
Título: dc.titleSpongiotic hyperplasia of the oral mucosa: case series and immunohistochemical analysis-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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