TEMPO-oxidized cellulose poly-ionic drawn fiber, a cell support system proof of concept

Registro completo de metadados
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Autor(es): dc.contributorUniversity of Araraquara-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorAalto Universitty-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.creatorRios, Mariana Alves-
Autor(es): dc.creatorBarbugli, Paula Aboud-
Autor(es): dc.creatorIemma, Mônica Rosas Costa-
Autor(es): dc.creatorGrande, Rafael-
Autor(es): dc.creatorCarvalho, Antônio José Felix-
Autor(es): dc.creatorTrovatti, Eliane-
Data de aceite: dc.date.accessioned2025-08-21T17:33:07Z-
Data de disponibilização: dc.date.available2025-08-21T17:33:07Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2021-10-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s10853-021-06373-4-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/229263-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/229263-
Descrição: dc.descriptionThe development of new cell carrier systems is crucial for application in regenerative medicine, once they deliver the cells to the injured tissue to trigger the repair and stimulate the regeneration. Here we report the preparation of a cell carrier system in fiber shape, in which the cells osteo-1 are incorporated. For the fiber formation, the oxidized cellulose nanofibers suspension loaded with cells is complexed with calcium ions in a pulling process giving rise to the fiber loaded with cells, with dimensions which allow it to handle. The microscopic images showed the success of the proposed method to incorporate the cells into the fibers. The results of the in vitro viability tests indicated the capability of the fibers to keep the cells alive and to mineralize them, indicating that their osteogenic capability was not affected. In addition, the fiber disintegration studies showed the system is capable of releasing the cells, suggesting the potential of the fibers as a new assembled hydrogel carrier cell therapy.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionUniversity of Araraquara, UNIARA, R. Carlos Gomes, 1217-
Descrição: dc.descriptionLaboratory of Confocal Microscopy Department of Dental Materials and Prosthodontics Faculty of Dentistry São Paulo State University (Unesp)-
Descrição: dc.descriptionDepartment of Bioproducts and Biosystems School of Chemical Engineering Aalto Universitty-
Descrição: dc.descriptionDepartment of Materials Engineering Sao Carlos School of Engineering University of Sao Paulo, Av. Joao Dagnone 1100-
Descrição: dc.descriptionLaboratory of Confocal Microscopy Department of Dental Materials and Prosthodontics Faculty of Dentistry São Paulo State University (Unesp)-
Descrição: dc.descriptionFAPESP: 2017/18782-6-
Descrição: dc.descriptionFAPESP: 2018/06555-8-
Descrição: dc.descriptionCNPq: 303847/2019-0-
Descrição: dc.descriptionCNPq: 307124/2015-0-
Formato: dc.format16661-16670-
Idioma: dc.languageen-
Relação: dc.relationJournal of Materials Science-
???dc.source???: dc.sourceScopus-
Título: dc.titleTEMPO-oxidized cellulose poly-ionic drawn fiber, a cell support system proof of concept-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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