Magnetic and highly luminescent heterostructures of gd3+/zno conjugated to gcis/zns quantum dots for multimodal imaging

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUNIV Angers-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.creatorda Silva, Bruna Lallo-
Autor(es): dc.creatorLemaire, Laurent-
Autor(es): dc.creatorBenoit, Jean-Pierre-
Autor(es): dc.creatorBorges, Fernanda Hediger-
Autor(es): dc.creatorGonçalves, Rogéria Rocha-
Autor(es): dc.creatorAmantino, Camila Fernanda-
Autor(es): dc.creatorPrimo, Fernando Lucas-
Autor(es): dc.creatorChiavacci, Leila Aparecida-
Data de aceite: dc.date.accessioned2025-08-21T18:44:43Z-
Data de disponibilização: dc.date.available2025-08-21T18:44:43Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2021-07-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/nano11071817-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/229120-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/229120-
Descrição: dc.descriptionIn recent years, the use of quantum dots (Qdots) to obtain biological images has attracted attention due to their excellent luminescent properties and the possibility of their association with contrast agents for magnetic resonance imaging (MRI). In this study, Gd3+/ZnO (ZnOGd) were conjugated with Qdots composed of a gadolinium-copper-indium-sulphur core covered with a ZnS shell (GCIS/ZnS Qdots). This conjugation is an innovation that has not yet been described in the literature, and which aims to improve Qdot photoluminescent properties. Structural and morphological Qdots features were obtained by transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and thermogravimetric analyses (TGA). The photoluminescent properties were examined by emission (PL) and excitation (PLE) spectra. A new ZnOGd and GCIS/ZnS (ZnOGd-GCIS/ZnS) nanomaterial was synthesized with tunable optical properties depending on the ratio between the two native Qdots. A hydrophilic or lipophilic coating, using 3-glycidyloxypropyltrimethoxysilane (GPTMS) or hexadecyltrimethoxysilane (HTMS) on the surface of ZnOGd-GCIS/ZnS Qdots, was carried out before assessing their efficiency as magnetic resonance contrast agents. ZnOGd-GCIS/ZnS had excellent luminescence and MRI properties. The new Qdots developed ZnOGd-GCIS/ZnS, mostly constituted of ZnOGd (75%), which had less cytotoxicity when compared to ZnOGd, as well as greater cellular uptake.-
Descrição: dc.descriptionDepartment of Drugs and Medicines School of Pharmaceutical Sciences São Paulo State University (UNESP), Highway Araraquara-Jaú-
Descrição: dc.descriptionMINT INSERM CNRS SFR-ICAT UNIV Angers-
Descrição: dc.descriptionPRISM SFR-ICAT UNIV Angers-
Descrição: dc.descriptionLaboratório de Materiais Luminescentes Micro e Nanoestruturados—Mater Lumen Departamento de Química FFCLRP Universidade de São Paulo (USP)-
Descrição: dc.descriptionDepartment of Drugs and Medicines School of Pharmaceutical Sciences São Paulo State University (UNESP), Highway Araraquara-Jaú-
Idioma: dc.languageen-
Relação: dc.relationNanomaterials-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCytotoxicity-
Palavras-chave: dc.subjectLuminescent properties-
Palavras-chave: dc.subjectMagnetic resonance imaging-
Palavras-chave: dc.subjectQuantum dots-
Título: dc.titleMagnetic and highly luminescent heterostructures of gd3+/zno conjugated to gcis/zns quantum dots for multimodal imaging-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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