Insights into differentiation and function of the transition region between the seminiferous tubule and rete testis

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Federal de Minas Gerais (UFMG)-
Autor(es): dc.contributorUniversity of Illinois-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversity of Port Harcourt-
Autor(es): dc.creatorFigueiredo, A. F.A.-
Autor(es): dc.creatorHess, Rex A.-
Autor(es): dc.creatorBatlouni, S. R.-
Autor(es): dc.creatorWnuk, N. T.-
Autor(es): dc.creatorTavares, A. O.-
Autor(es): dc.creatorAbarikwu, S. O.-
Autor(es): dc.creatorCosta, G. M.J.-
Autor(es): dc.creatorFrança, L. R.-
Data de aceite: dc.date.accessioned2025-08-21T20:20:36Z-
Data de disponibilização: dc.date.available2025-08-21T20:20:36Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2021-07-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.diff.2021.06.002-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/229070-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/229070-
Descrição: dc.descriptionSeminiferous tubules physically connect to the rete testis through short segments called the transition region (TR). During fetal development, this specialized junction is considered the initial site where testis cords begin to form and to grow in length well beyond birth and into adulthood and form convoluted tubular cores. Mitotic activity of the Sertoli cell, the somatic cell of the epithelium, ceases before puberty, but modified Sertoli cells in the TR remain immature and capable of proliferation. This review presents what is known about this specialized region of the testis, with an emphasis on the morphological, molecular and physiological features, which support the hypothesis that this short region of epithelial transition serves as a specialized niche for undifferentiated Sertoli cells and spermatogonial stem cells. Also, the region is populated by an elevated number of immune cells, suggesting an important activity in monitoring and responding to any leakage of autoantigens, as sperm enter the rete testis. Several structure/function characteristics of the transition region are discussed and compared across species.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG)-
Descrição: dc.descriptionLaboratory of Cellular Biology Department of Morphology Institute of Biological Sciences Federal University of Minas Gerais-
Descrição: dc.descriptionDepartment of Comparative Biosciences University of Illinois-
Descrição: dc.descriptionAquaculture Center (CAUNESP) São Paulo State University-
Descrição: dc.descriptionDepartment of Biochemistry University of Port Harcourt-
Descrição: dc.descriptionAquaculture Center (CAUNESP) São Paulo State University-
Formato: dc.format36-47-
Idioma: dc.languageen-
Relação: dc.relationDifferentiation-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectRete testis-
Palavras-chave: dc.subjectSeminiferous tubules-
Palavras-chave: dc.subjectSertoli cell-
Palavras-chave: dc.subjectSertoli valve-
Palavras-chave: dc.subjectTransition region-
Palavras-chave: dc.subjectTubuli recti-
Título: dc.titleInsights into differentiation and function of the transition region between the seminiferous tubule and rete testis-
Tipo de arquivo: dc.typevídeo-
Aparece nas coleções:Repositório Institucional - Unesp

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