Otosporin reduces pulp inflammatory reactions after dental bleaching of rat molars

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade Federal de Minas Gerais (UFMG)-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.creatorFerreira, Luciana Louzada-
Autor(es): dc.creatorBenetti, Francine-
Autor(es): dc.creatorÁlamo, Larissa-
Autor(es): dc.creatorBosisio, Ana Caroline-
Autor(es): dc.creatorde Proença, Ariane Santana-
Autor(es): dc.creatorRahal, Vanessa-
Autor(es): dc.creatorSipert, Carla Renata-
Autor(es): dc.creatorBriso, André Luiz Fraga-
Autor(es): dc.creatorCintra, Luciano Tavares Angelo-
Data de aceite: dc.date.accessioned2025-08-21T15:12:08Z-
Data de disponibilização: dc.date.available2025-08-21T15:12:08Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2019-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.14436/2358-2545.10.1.054-061.oar-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/228925-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/228925-
Descrição: dc.descriptionIntroduction: Patients undergoing dental bleaching relate to postoperative sensitivity, that is linked to hydrogen peroxide (H2O2) penetrating on the dental pulp. This study evaluated the anti-inflammatory effect of ibuprofen, Otosporin®, and curcumin gel on the pulp of the rats’ teeth after bleaching. Methods: Fifty rats were divided into CG: controlplacebo gel; BLE: bleached (35% H2O2, 30 minutes); BLE-I: bleached and ibuprofen oral administration (twice every 12 hours in 2 successive days); BLE-O: bleached followed by Otosporin® application in the molar surfaces (10 minutes); and BLE-C: bleaching session followed curcumin gel (10 minutes). After two days, the rats were killed for histological analysis. Statistical tests were performed (P<.05). Results: BLE, BLE-I, and BLE-C had severe inflammation or necrosis in the occlusal third of coronal pulp (P>.05); BLE-O had mild inflammation and was similar from CG (P>.05) and different from other groups (P<.05). In the middle third, BLE-O group had lower inflammatory infiltration and remained different from BLE group (P<.05); BLE, BLE-I, and BLE-C were similar (P>.05). In the cervical third, BLE, BLE-I, and BLE-C had a reduction of inflammation, without difference between bleached groups (P>.05). Conclusions: Otosporin® can reduce the inflammation in the pulp after dental bleaching; this result was not observed using ibuprofen or curcumin gel. Therefore, this study shows a new teeth bleaching posttreatment possibility using Otosporin®, which minimizes the inflammation generated to the pulp tissue by the bleaching gel. This could consequently minimize the postoperative sensitivity.-
Descrição: dc.descriptionUniversidade Estadual Paulista Faculdade de Odontologia de Araçatuba Departamento de Endodontia-
Descrição: dc.descriptionUniversidade Federal de Minas Gerais Faculdade de Odontologia Departamento de Odontologia Restauradora Endodontia-
Descrição: dc.descriptionUniversidade Estadual Paulista Faculdade de Odontologia de Araçatuba Departamento de Odontologia Restauradora-
Descrição: dc.descriptionUniversidade de São Paulo Faculdade de Odontologia Departamento de Endodontia-
Descrição: dc.descriptionUniversidade Estadual Paulista Faculdade de Odontologia de Araçatuba Departamento de Endodontia-
Descrição: dc.descriptionUniversidade Estadual Paulista Faculdade de Odontologia de Araçatuba Departamento de Odontologia Restauradora-
Formato: dc.format54-61-
Idioma: dc.languageen-
Relação: dc.relationDental Press Endodontics-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAnti-Inflammatory Agents-
Palavras-chave: dc.subjectDental Pulp-
Palavras-chave: dc.subjectHydrogen Peroxide-
Palavras-chave: dc.subjectTooth Bleaching-
Título: dc.titleOtosporin reduces pulp inflammatory reactions after dental bleaching of rat molars-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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