Coronavirus (SARS-CoV-2) and the risk of obesity for critically illness and ICU admitted: Meta-analysis of the epidemiological evidence

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Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorSchool of Dentistry-
Autor(es): dc.creatorSales-Peres, Silvia Helena de Carvalho-
Autor(es): dc.creatorde Azevedo-Silva, Lucas José-
Autor(es): dc.creatorBonato, Rafaela Carolina Soares-
Autor(es): dc.creatorSales-Peres, Matheus de Carvalho-
Autor(es): dc.creatorPinto, Ana Carolina da Silvia-
Autor(es): dc.creatorSantiago Junior, Joel Ferreira-
Data de aceite: dc.date.accessioned2025-08-21T20:08:49Z-
Data de disponibilização: dc.date.available2025-08-21T20:08:49Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2020-09-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.orcp.2020.07.007-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/228836-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/228836-
Descrição: dc.descriptionObjectives: To investigate the relationship between coronavirus disease 2019 (COVID-19) and obesity in critically ill patients admitted to the intensive care unit (ICU). Methods: We systematically searched PubMed, SCOPUS, Embase, LILACS, and Web of Science for studies published up to April 27, 2020. The outcome of interest was composite poor outcome, comprising mortality and severe COVID-19. We used a standardized data extraction form to collect information from published reports of eligible studies. Heterogeneity and publication bias were assessed using I2 statistic and funnel plots, respectively. Results: Nine studies including 6577 patients were selected for evaluation. The COVID-19 patients were 59.80% male and had comorbidities such as hypertension (51.51%), diabetes (30.3%), cardiovascular disease (16.66%), lung disease (15.99%), renal disease (7.49%), cancer (5.07%), and immunosuppression (1.8%). For patients with severe complications, the overall pooled event rates were 56.2% (random; 95% CI: 35.3–75.1; p = 0.015; I2 = 71.461) for obesity, 23.6% (random; 95% CI: 17.9–30.5; p = 0.000; I2 = 87.705) for type 2 diabetes, 45.9% (random; 95% CI: 38.0–53.9; p = 0.000; I2 = 90.152) for hypertension, 20.0% (random; 95% CI: 7.9–42.0; p = 0.000; I2 = 94.577) for smoking, 21.6% (random; 95% CI: 14.1–31.4%; p = 0.000, I2 = 92.983) for lung diseases, and 20.6% (random; 95% CI: 15.2–27.5; p = 0.000, I2 = 85.735) for cardiovascular diseases. Discussion: This systematic review indicated the relationship between obesity, ICU admission, severe COVID-19, and disease progression in patients with COVID-19. Obese patients with hypertension, type 2 diabetes, smoking habit, lung disease, and/or cardiovascular disease should be cared for with increased attention.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionDepartment of Pediatric Dentistry Orthodontics and Public Health Bauru School of Dentistry University of São Paulo, Al. Octávio Pinheiro Brisolla, 9-75, Vila Universitária-
Descrição: dc.descriptionDepartment of Prosthodontics and Periodontology Bauru School of Dentistry University of São Paulo, Al. Octávio Pinheiro Brisolla, 9-75, Vila Universitária-
Descrição: dc.descriptionDepartment of Plastic Surgery Botucatu Medical School-
Descrição: dc.descriptionSchool of Dentistry, Unisagrado-
Descrição: dc.descriptionDepartment of Plastic Surgery Botucatu Medical School-
Formato: dc.format389-397-
Idioma: dc.languageen-
Relação: dc.relationObesity Research and Clinical Practice-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCOVID-19-
Palavras-chave: dc.subjectHospitalization-
Palavras-chave: dc.subjectICU-
Palavras-chave: dc.subjectIntubation-
Palavras-chave: dc.subjectObesity-
Palavras-chave: dc.subjectSARS-CoV-2-
Título: dc.titleCoronavirus (SARS-CoV-2) and the risk of obesity for critically illness and ICU admitted: Meta-analysis of the epidemiological evidence-
Tipo de arquivo: dc.typevídeo-
Aparece nas coleções:Repositório Institucional - Unesp

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