In vivo efficacy of a biotherapic and eugenol formulation against Rhipicephalus microplus

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade Federal de Minas Gerais (UFMG)-
Autor(es): dc.creatorValente, Paula Pimentel-
Autor(es): dc.creatorMoreira, Gustavo Henrique Ferreira Abreu-
Autor(es): dc.creatorSerafini, Matheus Ferreira-
Autor(es): dc.creatorFacury-Filho, Elias Jorge-
Autor(es): dc.creatorCarvalho, Antônio Último-
Autor(es): dc.creatorFaraco, André Augusto Gomes-
Autor(es): dc.creatorCastilho, Rachel Oliveira-
Autor(es): dc.creatorRibeiro, Múcio Flávio Barbosa-
Data de aceite: dc.date.accessioned2025-08-21T23:41:46Z-
Data de disponibilização: dc.date.available2025-08-21T23:41:46Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2017-03-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s00436-016-5366-x-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/228267-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/228267-
Descrição: dc.descriptionThe control of Rhipicephalus microplus is essential to prevent cattle discomfort and economic losses. However, increased resistance and acaricides inefficiency lead producers to adopt strategies that could result in the accumulation of chemical residues in meat and milk with possibilities of poisoning in animals and people. This scenario demonstrates the necessity of research into the identification of novel, effective and environmentally safe therapeutic options for cattle tick control. The objectives of this study were to develop and assess the efficacy of R. microplus biotherapic and of 5% eugenol for the control of R. microplus in artificially infested calves. Eighteen male 6-month-old Holstein calves were divided into three groups of six animals. In Group 1, the animals did not receive medication (control group); in Group 2, the animals received 1 mL of R. microplus biotherapic at dilution 6CH (centesimal Hahnemannian), orally administered twice daily. And in Group 3, they received a single application of eugenol 5% in the pour-on formulation. The median efficacy for biotherapy and eugenol 5% was respectively 10.13 and 13.97%; however, upon analyzing reproductive efficiency, it is noteworthy that the biotherapic had 45.86% efficiency and was superior to the action of eugenol (12.03%) after 37 days of treatment. The ultrastructural study provided information about the effects of R. microplus biotherapic on the ovaries of engorged females and showed disorganization in the deposition of the oocyte exochorion. The results suggest hatchability inhibition of larvae, interference in R. microplus reproduction and future possibilities for eco-friendly control of R. microplus with biotherapic 6CH.-
Descrição: dc.descriptionDepartamento de Zootecnia Universidade Estadual de São Paulo Faculdade de Ciências Agrárias e Veterinárias, Rodovia Professor Paulo Donato Castellane s/n-
Descrição: dc.descriptionDepartamento de Clínica Veterinária Escola de Veterinária Universidade Federal de Minas Gerais-
Descrição: dc.descriptionDepartamento de Fitoquímica Faculdade de Farmácia Universidade Federal de Minas Gerais-
Descrição: dc.descriptionDepartamento de Parasitologia Instituto de Ciências Biológicas Universidade Federal de Minas Gerais-
Descrição: dc.descriptionDepartamento de Zootecnia Universidade Estadual de São Paulo Faculdade de Ciências Agrárias e Veterinárias, Rodovia Professor Paulo Donato Castellane s/n-
Formato: dc.format929-938-
Idioma: dc.languageen-
Relação: dc.relationParasitology Research-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCattle tick-
Palavras-chave: dc.subjectEco-friendly control-
Palavras-chave: dc.subjectHomeopathy-
Palavras-chave: dc.subjectPour on-
Palavras-chave: dc.subjectUltrastructure-
Título: dc.titleIn vivo efficacy of a biotherapic and eugenol formulation against Rhipicephalus microplus-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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