Intake of sucrose solution and paradoxical sleep deprivation in the rat

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorPezzato, Fernanda Augustini-
Autor(es): dc.creatorDe Paula, Hugo Garrido Medeiros-
Autor(es): dc.creatorBosqueiro, José Roberto-
Autor(es): dc.creatorHoshino, Katsumasa-
Data de aceite: dc.date.accessioned2025-08-21T22:15:00Z-
Data de disponibilização: dc.date.available2025-08-21T22:15:00Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2009-12-01-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/227507-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/227507-
Descrição: dc.descriptionBackground: Paradoxical sleep deprivation (PSD) is known for its antidepressive property, both in humans and experimental animals. The small platform method used to promote PSD in rats, however, involves stress similar to that observed in the methods used to induce depressive-like state. Objective and methods: As sucrose solution intake is validated as a depressive-state marker in the rat, the present study evaluated such parameter before, during and after PSD carried out by the small platform method. Results: The daily mean sucrose solution (15%) ingested by a group of 11 adult male Wistar rats was progressively reduced with PSD. The daily fall in sucrose intake was statistically significant (t-test, p<0.05) from baseline, except in the second day of PSD. The development of taste aversion does not explain the reduction in sucrose intake, since its consumption, 2 days after the end of 4 days of PSD (n=5), was similar to baseline levels. PSD until the animals ceased to stay on the platform (n=6) showed to promote deaths in the recovery period with low consumption of sucrose. Conclusion: The relationship of the data obtained with the development of anhedonia and carbohidrate metabolism opens new interesting aspects for investigation.-
Descrição: dc.descriptionDepartamento de Ciências Biológicas Universidade Estadual de São Paulo (UNESP), Bauru (SP)-
Descrição: dc.descriptionDepartamento de Ciências Biológicas Universidade Estadual de São Paulo (UNESP), Bauru (SP)-
Formato: dc.format125-129-
Idioma: dc.languageen-
Relação: dc.relationSleep Science-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAnhedonia-
Palavras-chave: dc.subjectMethod-
Palavras-chave: dc.subjectRats-
Palavras-chave: dc.subjectSleep deprivation-
Palavras-chave: dc.subjectStress-
Palavras-chave: dc.subjectSucrose intake-
Título: dc.titleIntake of sucrose solution and paradoxical sleep deprivation in the rat-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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