Evaluation of tissue reaction to Aroeira (Myracrodruon urundeuva) extracts: A histologic and edemogenic study

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.creatorMachado, Alessandra Cury-
Autor(es): dc.creatorDezan Jr., Eloi-
Autor(es): dc.creatorGomes-Filho, João Eduardo-
Autor(es): dc.creatorCintra, Luciano Tavares Angelo-
Autor(es): dc.creatorRuviére, Denise Belucio-
Autor(es): dc.creatorZoccal, Renata-
Autor(es): dc.creatorDamante, Carla Andreotti-
Autor(es): dc.creatorJardim Júnior, Elerson Gaetti-
Data de aceite: dc.date.accessioned2025-08-21T16:24:50Z-
Data de disponibilização: dc.date.available2025-08-21T16:24:50Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2012-01-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1590/S1678-77572012000400005-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/226987-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/226987-
Descrição: dc.descriptionObjectiveS: This study evaluated subcutaneous tissue response to Aroeira (Myracrodruon urundeuva) extract employing edemogenic and histological analyses. Material and Methods: Test groups consisted of aqueous and ethanolic Aroeira extracts and saline (control). For edema quantification, 18 rats received an intravenous injection of Evan's Blue. After 30 min, the extracts and saline were injected on the dorsum of the rats, which were then sacrificed after 3 and 6 h. Readings were performed in a spectrophotometer. For subcutaneous implantation, 30 rats received a polyethylene tube containing the extracts on their dorsum and then they were killed after 7 and 28 days. The samples were processed for histological analysis and evaluated with a light microscope. The inflammatory infiltrate was quantified. Results: There were no statistically significant differences between aqueous extract and saline groups in relation to edema quantification in the different periods (p>0.05). Ethanolic solution resulted in more edema independently of the experimental period (p<0.05). Histological analysis showed similar results on the 7-day period for the 3 groups. There was a notable reduction on inflammatory cell number for saline and aqueous extract groups at 28 days. Conclusion: The aqueous extract showed biocompatible properties similar to those of saline.-
Descrição: dc.descriptionDepartment of Pediatrics Araçatuba School of Dentistry UNESP - Univ. Estadual Paulista, Araçatuba, SP-
Descrição: dc.descriptionDepartment of Endodontics Araçatuba School of Dentistry UNESP - Univ. Estadual Paulista, Rua José Bonifácio, 1193, Araçatuba - SP, 16.015-050-
Descrição: dc.descriptionDepartment of Periodontology Bauru School of Dentistry University of São Paulo, Bauru, SP-
Descrição: dc.descriptionDepartment of Microbiology Araçatuba School of Dentistry UNESP - Univ. Estadual Paulista, Araçatuba, SP-
Descrição: dc.descriptionDepartment of Pediatrics Araçatuba School of Dentistry UNESP - Univ. Estadual Paulista, Araçatuba, SP-
Descrição: dc.descriptionDepartment of Endodontics Araçatuba School of Dentistry UNESP - Univ. Estadual Paulista, Rua José Bonifácio, 1193, Araçatuba - SP, 16.015-050-
Descrição: dc.descriptionDepartment of Microbiology Araçatuba School of Dentistry UNESP - Univ. Estadual Paulista, Araçatuba, SP-
Formato: dc.format414-418-
Idioma: dc.languageen-
Relação: dc.relationJournal of Applied Oral Science-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAnacardiaceae-
Palavras-chave: dc.subjectEdema-
Palavras-chave: dc.subjectInflammation-
Palavras-chave: dc.subjectMedicinal plants-
Título: dc.titleEvaluation of tissue reaction to Aroeira (Myracrodruon urundeuva) extracts: A histologic and edemogenic study-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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