Efecto del aceite esencial de Citrus aurantium L. en la regeneración muscular en ratones mdx

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade Estadual de Campinas (UNICAMP)-
Autor(es): dc.creatorde Souza, Paula Aiello Tomé-
Autor(es): dc.creatorMarques, Maria Júlia-
Autor(es): dc.creatorLima, Clélia Akiko Hiruma-
Autor(es): dc.creatorMatheus, Selma Maria Michelin-
Data de aceite: dc.date.accessioned2025-08-21T15:30:51Z-
Data de disponibilização: dc.date.available2025-08-21T15:30:51Z-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2022-04-29-
Data de envio: dc.date.issued2011-01-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.4067/S0717-95022011000400048-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/226750-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/226750-
Descrição: dc.descriptionDuchenne muscular dystrophy (DMD) is a severe X-linked recessive disorder characterized by the progressive loss of muscular strength. Mdx mutant mice show a marked deficiency in dystrophin, which was related to muscle membrane stability. The aim of this study was to verify the possible protective anti-inflammatory effect of citrus oil on mdx muscle fibers. Thus, adult male and female mdx mice (014/06-CEEA) were divided into control and citrus-treated. After 60 days of treatment, one ml of blood was collected for creatine kinase (CK) test. Diaphragm, sternomastoideus, anterior tibial and gastrocnemius muscles were removed and processed according to histological routine methods. The observed alterations indicate a direct effect of citrus. Recent studies have improved the diagnosis of muscular diseases but with no definitions of efficient treatments. Intervention with several therapies is important to many patients presenting muscular dystrophy, which enables them to live longer and be more active, while there is no development of gene therapies.-
Descrição: dc.descriptionDepartment of Morphology Institute of Biosciences São Paulo State University (UNESP), Botucatu Municipality, São Paulo State-
Descrição: dc.descriptionDepartment of Anatomy Institute of Biology State University of Campinas (UNICAMP), Campinas Municipality, São Paulo State-
Descrição: dc.descriptionDepartment of Physiology Institute of Biosciences São Paulo State University (UNESP), Botucatu Municipality, São Paulo State-
Descrição: dc.descriptionDepartment of Morphology Institute of Biosciences São Paulo State University (UNESP), Botucatu Municipality, São Paulo State-
Descrição: dc.descriptionDepartment of Physiology Institute of Biosciences São Paulo State University (UNESP), Botucatu Municipality, São Paulo State-
Formato: dc.format1357-1363-
Idioma: dc.languageen-
Idioma: dc.languagees-
Relação: dc.relationInternational Journal of Morphology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCentral nuclei-
Palavras-chave: dc.subjectCitrus aurantium L.-
Palavras-chave: dc.subjectCreatine kinase-
Palavras-chave: dc.subjectDuchenne muscular dystrophy-
Palavras-chave: dc.subjectMdx mouse-
Palavras-chave: dc.subjectMuscle fiber-
Palavras-chave: dc.subjectMuscle regeneration-
Título: dc.titleEfecto del aceite esencial de Citrus aurantium L. en la regeneración muscular en ratones mdx-
Título: dc.titleEffect of Citrus aurantium L. essential oil on muscle regeneration in mdx mice-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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