Mucoadhesive drug delivery systems

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade Estadual de Maringá (UEM)-
Autor(es): dc.creatorCarvalho, Flávia Chiva-
Autor(es): dc.creatorBruschi, Marcos Luciano-
Autor(es): dc.creatorEvangelista, Raul Cesar-
Autor(es): dc.creatorGremião, Maria Palmira Daflon-
Data de aceite: dc.date.accessioned2025-08-21T19:51:56Z-
Data de disponibilização: dc.date.available2025-08-21T19:51:56Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2010-01-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1590/S1984-82502010000100002-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/225870-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/225870-
Descrição: dc.descriptionDrug actions can be improved by developing new drug delivery systems, such as the mucoadhesive system. These systems remain in close contact with the absorption tissue, the mucous membrane, releasing the drug at the action site leading to a bioavailability increase and both local and systemic effects. Mucoadhesion is currently explained by six theories: electronic, adsorption, wettability, diffusion, fracture and mechanical. Several in vitro and in vivo methodologies are proposed for studying its mechanisms. However, mucoadhesion is not yet well understood. The aim of this study was to review the mechanisms and theories involved in mucoadhesion, as well as to describe the most-used methodologies and polymers in mucoadhesive drug delivery systems.-
Descrição: dc.descriptionPharmaceutical Sciences Postgraduate Program School of Pharmaceutical Sciences São Paulo State University-
Descrição: dc.descriptionDepartment of Pharmacy State University of Maringá UEM-
Descrição: dc.descriptionDepartment of Drugs and Pharmaceuticals School of Pharmaceutical Sciences São Paulo State University-
Descrição: dc.descriptionPharmaceutical Sciences Postgraduate Program School of Pharmaceutical Sciences São Paulo State University-
Descrição: dc.descriptionDepartment of Drugs and Pharmaceuticals School of Pharmaceutical Sciences São Paulo State University-
Formato: dc.format1-17-
Idioma: dc.languageen-
Relação: dc.relationBrazilian Journal of Pharmaceutical Sciences-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBioadhesion-
Palavras-chave: dc.subjectDrugs/delivery-
Palavras-chave: dc.subjectMucoadhesion-
Palavras-chave: dc.subjectMucoadhesive systems-
Título: dc.titleMucoadhesive drug delivery systems-
Tipo de arquivo: dc.typevídeo-
Aparece nas coleções:Repositório Institucional - Unesp

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