Protective efficacy of Psidium cattleianum and Myracrodruon urundeuva aqueous extracts against caries development in rats

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorCrivelaro De Menezes, Taís Elisabete-
Autor(es): dc.creatorBotazzo Delbem, Alberto Carlos-
Autor(es): dc.creatorLourenção Brighenti, Fernanda-
Autor(es): dc.creatorCluádia Okamoto, Ana-
Autor(es): dc.creatorJardim Júnior, Elerson Gaetti-
Data de aceite: dc.date.accessioned2025-08-21T23:12:51Z-
Data de disponibilização: dc.date.available2025-08-21T23:12:51Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2010-03-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3109/13880200903122202-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/225777-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/225777-
Descrição: dc.descriptionThis study evaluated the influence of Psidium cattleianum Sabine (Myrtaceae) and Myracrodruon urundeuva Allemão (Anacardiaceae) aqueous extracts on S. mutans counts and dental enamel micro-hardness of rats submitted to a cariogenic challenge. Sixty Wistar rats were distributed in three groups and received water (control) or aqueous extracts of Psidium cattleianum or Myracrodruon urundeuva as hydration solution. Initially the animals had their sublingual and submandibular salivary glands surgically removed and the parotid ducts ligated. Then the rats were inoculated with 10 6 CFU of Streptococcus mutans ATCC 35668 and were fed with a cariogenic diet. To detect and quantify the presence of S. mutans, oral biofilms were sampled and microbial DNA was extracted and submitted to amplification by means of real-time PCR (Polymerase Chain Reaction). After seven weeks the animals were sacrificed and enamel demineralization was analyzed by cross-sectional micro-hardness. Both extracts produced a significant reduction on S. mutans counts and decreased the enamel demineralization. It can be concluded that the extracts tested had a significant effect on S. mutans in oral biofilm of the rats, decreasing S. mutans accumulation and enamel demineralization. © 2010 Informa UK Ltd.-
Descrição: dc.descriptionDepartment of Pediatric Dentistry São Paulo State University UNESP, Araçatuba-
Descrição: dc.descriptionDepartment of Pathology and Oral Diagnostics São Paulo State University UNESP, Araçatuba-
Descrição: dc.descriptionDepartment of Pediatric Dentistry São Paulo State University UNESP, Araçatuba-
Descrição: dc.descriptionDepartment of Pathology and Oral Diagnostics São Paulo State University UNESP, Araçatuba-
Formato: dc.format300-305-
Idioma: dc.languageen-
Relação: dc.relationPharmaceutical Biology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAntibacterial agents-
Palavras-chave: dc.subjectDental caries-
Palavras-chave: dc.subjectNatural products-
Palavras-chave: dc.subjectStreptococcus mutans-
Título: dc.titleProtective efficacy of Psidium cattleianum and Myracrodruon urundeuva aqueous extracts against caries development in rats-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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